Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia
With the increase in large multimodal cohorts and high‐throughput technologies, the
potential for discovering novel biomarkers is no longer limited by data set size. Artificial …
potential for discovering novel biomarkers is no longer limited by data set size. Artificial …
Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient selection and biomarkers
Clinical trials in dementia with Lewy bodies: the evolving c... : Current Opinion in Neurology
Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient …
Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient …
Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer's disease
F Gonzalez-Ortiz, BE Kirsebom, J Contador… - Nature …, 2024 - nature.com
Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration
could identify individuals at risk for cognitive decline in Alzheimer's disease (AD). In blood …
could identify individuals at risk for cognitive decline in Alzheimer's disease (AD). In blood …
Head-to-head study of diagnostic accuracy of plasma and cerebrospinal fluid p-tau217 versus p-tau181 and p-tau231 in a memory clinic cohort
Background and objective Phosphorylated tau (p-tau) 217 has recently received attention
because it seems more reliable than other p-tau variants for identifying Alzheimer's disease …
because it seems more reliable than other p-tau variants for identifying Alzheimer's disease …
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease neuropathology
PR Kac, F González-Ortiz, A Emeršič… - Nature …, 2024 - nature.com
Blood phosphorylated tau (p-tau) biomarkers, including p-tau217, show high associations
with Alzheimer's disease (AD) neuropathologic change and clinical stage. Certain plasma p …
with Alzheimer's disease (AD) neuropathologic change and clinical stage. Certain plasma p …
A cross-sectional study of Alzheimer-related proteins in women with polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in women of
reproductive age, and several risk factors found in PCOS are associated with an increased …
reproductive age, and several risk factors found in PCOS are associated with an increased …
A novel ultrasensitive assay for plasma p‐tau217: performance in individuals with subjective cognitive decline and early Alzheimer's disease
F Gonzalez‐Ortiz, PCL Ferreira… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Detection of Alzheimer's disease (AD) pathophysiology among individuals
with mild cognitive changes and those experiencing subjective cognitive decline (SCD) …
with mild cognitive changes and those experiencing subjective cognitive decline (SCD) …
Novel aspects of the phosphorylation and structure of pathological tau: implications for tauopathy biomarkers
T Kimura, H Sato, M Kano, L Tatsumi… - FEBS Open bio, 2024 - Wiley Online Library
The deposition of highly phosphorylated and aggregated tau is a characteristic of
tauopathies, including Alzheimer's disease. It has long been known that different isoforms of …
tauopathies, including Alzheimer's disease. It has long been known that different isoforms of …
Combining plasma Aβ and p-tau217 improves detection of brain amyloid in non-demented elderly
Y Niimi, S Janelidze, K Sato, N Tomita… - Alzheimer's Research & …, 2024 - Springer
Background Maximizing the efficiency to screen amyloid-positive individuals in
asymptomatic and non-demented aged population using blood-based biomarkers is …
asymptomatic and non-demented aged population using blood-based biomarkers is …
Exploring the potential of fully automated LUMIPULSE G plasma assays for detecting Alzheimer's disease pathology
A Silva-Spínola, MJ Leitão, A Nadal… - Alzheimer's Research & …, 2024 - Springer
Background LUMIPULSE G-automated immunoassays represent a widely used method for
the quantification of Alzheimer's disease (AD) biomarkers in the cerebrospinal fluid (CSF) …
the quantification of Alzheimer's disease (AD) biomarkers in the cerebrospinal fluid (CSF) …