TFOS DEWS II management and therapy report
The members of the Management and Therapy Subcommittee undertook an evidence-
based review of current dry eye therapies and management options. Management options …
based review of current dry eye therapies and management options. Management options …
TFOS DEWS II pain and sensation report
Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …
In vivo confocal microscopy of corneal nerves in health and disease
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …
[HTML][HTML] Advances in the diagnosis and treatment of dry eye
T Kojima, M Dogru, M Kawashima, S Nakamura… - Progress in retinal and …, 2020 - Elsevier
The core mechanism of dry eye is the tear film instability. Tear film-oriented diagnosis
(TFOD) is a concept to clarify the cause of tear film instability by tear film, and tear film …
(TFOD) is a concept to clarify the cause of tear film instability by tear film, and tear film …
Neuropathic pain and dry eye
Dry eye is a common, multifactorial disease currently diagnosed by a combination of
symptoms and signs. Its epidemiology and clinical presentation have many similarities with …
symptoms and signs. Its epidemiology and clinical presentation have many similarities with …
TFOS Lifestyle: Impact of elective medications and procedures on the ocular surface
The word “elective” refers to medications and procedures undertaken by choice or with a
lower grade of prioritization. Patients usually use elective medications or undergo elective …
lower grade of prioritization. Patients usually use elective medications or undergo elective …
Understanding neuropathic corneal pain—gaps and current therapeutic approaches
S Goyal, P Hamrah - Seminars in ophthalmology, 2016 - Taylor & Francis
The richly innervated corneal tissue is one of the most powerful pain generators in the body.
Corneal neuropathic pain results from dysfunctional nerves causing perceptions such as …
Corneal neuropathic pain results from dysfunctional nerves causing perceptions such as …
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …
their important roles in the maintenance of nerves in both homeostasis and inflammation …
Morphological and functional changes of corneal nerves and their contribution to peripheral and central sensory abnormalities
A Guerrero-Moreno, C Baudouin… - Frontiers in cellular …, 2020 - frontiersin.org
The cornea is the most densely innervated and sensitive tissue in the body. The cornea is
exclusively innervated by C-and A-delta fibers, including mechano-nociceptors that are …
exclusively innervated by C-and A-delta fibers, including mechano-nociceptors that are …
Neuropathic corneal pain: approaches for management
G Dieckmann, S Goyal, P Hamrah - Ophthalmology, 2017 - Elsevier
Neuropathic pain is caused by a primary lesion or dysfunction of the nervous system and
can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined …
can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined …