Abnormal metabolism is a hallmark of cancer cells. Accumulating evidence suggests that
metabolic changes are likely to occur before other cellular responses in cancer cells upon …

Cancer represents an extremely complicated ecosystem where cancer cells communicate
with non-cancer cells present in the tumour niche through intercellular contacts, paracrine …

To understand the molecular association between inflammation and dysregulated
metabolism in glioblastoma, the effect of IL-1β on Hexokinase 2 (HK2) expression was …

In recent years, it has been demonstrated that malignancy arises and advances through the
molecular interplay between tumor cells and non-malignant elements of the tumor stroma …

Purpose Ovarian cancer is the most lethal gynecologic malignancy. Resistance to platinum-
based chemotherapy affects the overall survival of patients. This study used an integrated …

From attributing mutations to cancers with the advent of cutting-edge genetic technology in
recent decades, to re-searching the age-old theory of intrinsic metabolic shift of cancers …

During lactation, an improper glucose supply often threatens mammary gland (MG) health.
However, information is limited on the metabolic trajectories and molecules that regulate …

Hace casi un siglo que se hipotetizó la asociación entre la diabetes y el cáncer. Hoy,
numerosos estudios epidemiológicos sostienen que las poblaciones con obesidad y/o …

Objective Many aggressive head and neck cancers contain 2 metabolically coupled tumor
compartments: a glycolytic stromal compartment with low caveolin-1 (CAV1) and high …

Tumor necrosis factor (TNF)-related apoptosis‑inducing ligand (TRAIL) is expressed in
ovarian tissue and is widely thought to exhibit strong antitumor activity in a variety of tumor …