Physiological angiogenesis occurs during embryogenesis, wound healing and reproductive
functions in adults. Abnormal angiogenesis takes place in certain chronic diseases …

Simple Summary In this review, we present knowledge of the molecular mechanisms and
therapeutic strategies of bone metastasis of breast cancer, particularly the interaction …

Objective: To evaluate the effects of curcumin on matrixmetalloproteinase-9 (MMP-9) and
invasion ability induced by transforming growth factor-β1 (TGF-β1) in MDA-MB-231 cells and …

Purpose: Skeletal metastases affect up to 85% of breast cancer patients by the time of their
death. This prospective in vivo study evaluated the diagnostic performance of computed …

Background Cancer patients are likely to undergo osteoporosis as consequence of hormone
manipulation and/or chemotherapy. Little is known about possible increased risk of fracture …

Purpose: CASP-3 gene gives rise, by alternative splicing to a caspase-3s variant, to the
antagonist apoptotic property of caspase-3. Deregulation of splicing in tumor cells favoring …

Purpose: Pathologic fractures could be prevented if reliable methods of fracture risk
assessment were available. A multicenter prospective study was conducted to identify …

Recent years have seen an increased effort in the development of peptide based
radiopharmaceuticals for nuclear medicine applications in imaging and therapy. This field is …

Radiolabeled peptide-based formulations are being evaluated for their application in
oncological imaging and therapy using nuclear medicine techniques. A major breakthrough …

Introduction In the present study, we investigated the potential for routine staging computed
tomography (CT) to assess fracture risk in breast cancer patients. Patients and Methods A …