Bench to bedside molecular functional imaging in translational cancer medicine: to image or to imagine?

A Mahajan, V Goh, S Basu, R Vaish, AJ Weeks… - Clinical radiology, 2015 - Elsevier
Ongoing research on malignant and normal cell biology has substantially enhanced the
understanding of the biology of cancer and carcinogenesis. This has led to the development …

RNAi-mediated SYT14 knockdown inhibits the growth of human glioma cell line U87MG

B Sheng, Y Jiang, D Wu, N Lai, Z Ye, B Zhang… - Brain Research …, 2018 - Elsevier
Abstract SYT14 (Synaptotagmin 14) participates in pathomechanical neurodegeneration
and contributes to abnormal neurodevelopment. However, the functional mechanism of …

Feasibility study of a point‐of‐care positron emission tomography system with interactive imaging capability

J Jiang, K Li, S Komarov, JA O'Sullivan… - Medical …, 2019 - Wiley Online Library
Purpose We investigated the feasibility of a novel positron emission tomography (PET)
system that provides near real‐time feedback to an operator who can interactively scan a …

PET and SPECT imaging for the acceleration of anti-cancer drug development

C RT Hillyar, JC Knight, KA Vallis… - Current Drug …, 2015 - ingentaconnect.com
Lead-compound optimization is an iterative process in the cancer drug development
pipeline, in which small molecule inhibitors or biological compounds that are selected for …