Effect of adult-born immature granule cells on pattern separation in the hippocampal dentate gyrus
SY Kim, W Lim - Cognitive Neurodynamics, 2024 - Springer
Young immature granule cells (imGCs) appear via adult neurogenesis in the hippocampal
dentate gyrus (DG). In comparison to mature GCs (mGCs)(born during development), the …
dentate gyrus (DG). In comparison to mature GCs (mGCs)(born during development), the …
Developmental and adult GAP-43 deficiency in mice dynamically alters hippocampal neurogenesis and mossy fiber volume
SE Latchney, I Masiulis, KJ Zaccaria… - Developmental …, 2014 - karger.com
Abstract Growth-associated protein-43 (GAP-43) is a presynaptic protein that plays key roles
in axonal growth and guidance and in modulating synapse formation. Previous work has …
in axonal growth and guidance and in modulating synapse formation. Previous work has …
Population and individual firing behaviors in sparsely synchronized rhythms in the hippocampal dentate gyrus
SY Kim, W Lim - Cognitive Neurodynamics, 2022 - Springer
We investigate population and individual firing behaviors in sparsely synchronized rhythms
(SSRs) in a spiking neural network of the hippocampal dentate gyrus (DG). The main …
(SSRs) in a spiking neural network of the hippocampal dentate gyrus (DG). The main …
Cognitive insight is associated with cortical thickness in first-episode psychosis
Compared to non-clinical subjects, people with psychosis show poor cognitive insight as
reflected in low Self-Reflectiveness and high Self-Certainty. Neuroimaging studies have …
reflected in low Self-Reflectiveness and high Self-Certainty. Neuroimaging studies have …
Spatial pattern separation differences in older adult carriers and non-carriers for the apolipoprotein E epsilon 4 allele
DP Sheppard, LV Graves, HM Holden… - Neurobiology of learning …, 2016 - Elsevier
We examined the performance of healthy young (n= 57) and older adults (n= 43) genotyped
as apolipoprotein E-ε4 (APOE-ε4) carriers or APOE-ε4 non-carriers on a delayed match-to …
as apolipoprotein E-ε4 (APOE-ε4) carriers or APOE-ε4 non-carriers on a delayed match-to …
Post-traumatic stress disorder is associated with altered modulation of prefrontal alpha band oscillations during working memory
M Popescu, EA Popescu, TJ DeGraba… - Clinical …, 2019 - Elsevier
Objective To investigate the relationship between the severity of PTSD symptoms,
modulation of alpha band oscillations, and behavioral performance in a working memory …
modulation of alpha band oscillations, and behavioral performance in a working memory …
Modeling contextual modulation of memory associations in the hippocampus
We present a computational model of how memories can be contextually acquired and
recalled in the hippocampus. Our adaptive contextual memory model comprises the lateral …
recalled in the hippocampus. Our adaptive contextual memory model comprises the lateral …
Intrahippocampal pathways involved in learning/memory mechanisms are affected by intracerebral infusions of amyloid-β 25-35 peptide and hydrated fullerene C 60 …
R Gordon, I Podolski, E Makarova… - Journal of …, 2017 - content.iospress.com
Primary memory impairments associated with increased level of amyloid-ß (Aß) in the brain
have been shown to be linked, partially, with early pathological changes in the entorhinal …
have been shown to be linked, partially, with early pathological changes in the entorhinal …
Corneal kindled C57BL/6 mice exhibit saturated dentate gyrus long-term potentiation and associated memory deficits in the absence of overt neuron loss
GJ Remigio, JL Loewen, S Heuston, C Helgeson… - Neurobiology of …, 2017 - Elsevier
Memory deficits have a significant impact on the quality of life of patients with epilepsy and
currently no effective treatments exist to mitigate this comorbidity. While these cognitive …
currently no effective treatments exist to mitigate this comorbidity. While these cognitive …
Less is more: Smaller hippocampal subfield volumes predict greater improvements in posttraumatic stress disorder symptoms over 2 years.
Posttraumatic stress disorder (PTSD) is a heterogeneous disorder, and symptom severity
varies over time. Neurobiological factors that predict PTSD symptoms and their chronicity …
varies over time. Neurobiological factors that predict PTSD symptoms and their chronicity …