[HTML][HTML] Insights and opportunities for deep brain stimulation as a brain circuit intervention

WJ Neumann, A Horn, AA Kühn - Trends in Neurosciences, 2023 - cell.com
Deep brain stimulation (DBS) is an effective treatment and has provided unique insights into
the dynamic circuit architecture of brain disorders. This Review illustrates our current …

Deep brain stimulation for refractory status dystonicus in children: multicenter case series and systematic review

LM Vogt, H Yan, B Santyr, S Breitbart… - Annals of …, 2024 - Wiley Online Library
Objective We sought to better understand the workflow, outcomes, and complications of
deep brain stimulation (DBS) for pediatric status dystonicus (SD). We present a systematic …

[HTML][HTML] Lead-DBS v3. 0: Mapping deep brain stimulation effects to local anatomy and global networks

C Neudorfer, K Butenko, S Oxenford, N Rajamani… - Neuroimage, 2023 - Elsevier
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …

[HTML][HTML] Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation

B Hollunder, JL Ostrem, IA Sahin, N Rajamani… - Nature …, 2024 - nature.com
Frontal circuits play a critical role in motor, cognitive and affective processing, and their
dysfunction may result in a variety of brain disorders. However, exactly which frontal …

[HTML][HTML] Head movement dynamics in dystonia: a multi-centre retrospective study using visual perceptive deep learning

R Peach, M Friedrich, L Fronemann… - npj Digital …, 2024 - nature.com
Dystonia is a neurological movement disorder characterised by abnormal involuntary
movements and postures, particularly affecting the head and neck. However, current clinical …

Connectivity profile for subthalamic nucleus deep brain stimulation in early stage Parkinson disease

ML Hacker, N Rajamani, C Neudorfer… - Annals of …, 2023 - Wiley Online Library
Objective This study was undertaken to describe relationships between electrode
localization and motor outcomes from the subthalamic nucleus (STN) deep brain stimulation …

[HTML][HTML] Gastrointestinal and hepatic diseases during the COVID-19 pandemic: Manifestations, mechanism and management

DZ Mohamed, MES Ghoneim… - World journal of …, 2021 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered the
causative pathogen of coronavirus disease 2019 (COVID-19) and has become an …

Deep brain stimulation for obsessive-compulsive disorder: optimal stimulation sites

GM Meyer, B Hollunder, N Li, K Butenko, TA Dembek… - Biological …, 2024 - Elsevier
Background Deep brain stimulation (DBS) is a promising treatment option for treatment-
refractory obsessive-compulsive disorder (OCD). Several stimulation targets have been …

[HTML][HTML] New developments in diagnostics and treatment of adult-onset focal dystonia

LM Centen, ME Van Egmond… - Current opinion in …, 2023 - journals.lww.com
Accurate phenotyping and (sub) classification of patients with dystonia is important for
improving diagnosis, subsequent treatment effect and population-based study outcomes in …

Influence of charges deposited on membranes of human hyperdirect pathway axons on depolarization during subthalamic deep brain stimulation

SN Makaroff, AR Nummenmaa… - Journal of Neural …, 2023 - iopscience.iop.org
Objective. The motor hyperdirect pathway (HDP) is a key target in the treatment of
Parkinson's disease with deep brain stimulation (DBS). Biophysical models of HDP DBS …