Bile acids, which are steroid molecules originating from cholesterol and synthesized in the
liver, play a pivotal role in regulating glucose metabolism and maintaining energy balance …

Bitter taste sensing is mediated by type 2 taste receptors (TAS2Rs (also known as T2Rs)),
which represent a distinct class of G-protein-coupled receptors. Among the 26 members of …

Many animal and plant species synthesize toxic compounds as deterrent; thus, detection of
these compounds is of vital importance to avoid their ingestion. Often, such compounds are …

Targeting inflammation and the pathways linking inflammation with cancer is an innovative
therapeutic strategy. Tastants are potential candidates for this approach, since taste …

A bitter-taste receptor activated in a surprising way Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Skin diseases represent a global healthcare challenge due to their rising incidence and
substantial socio-economic burden. While biological, immunological, and targeted therapies …

Acute graft-versus-host disease (aGVHD) is primarily driven by allogeneic donor T cells
associated with an altered composition of the host gut microbiome and its metabolites. The …

Bitter compounds are common in nature and among drugs. Previously, machine learning
tools were developed to predict bitterness from the chemical structure. However, known …

In the past, taste interactions between sodium chloride (NaCl) and bitter tastants were
investigated in human sensory studies, and the suppression of bitterness by sodium was …

Taste, food, and health are terms that have since always accompanied the act of eating, but
the association was simple: taste serves to classify a food as good or bad and therefore …