Research progress on the relationship between bile acid metabolism and type 2 diabetes mellitus
Y Hou, X Zhai, X Wang, Y Wu, H Wang, Y Qin… - Diabetology & Metabolic …, 2023 - Springer
Bile acids, which are steroid molecules originating from cholesterol and synthesized in the
liver, play a pivotal role in regulating glucose metabolism and maintaining energy balance …
liver, play a pivotal role in regulating glucose metabolism and maintaining energy balance …
Bitter taste receptor activation by cholesterol and an intracellular tastant
Bitter taste sensing is mediated by type 2 taste receptors (TAS2Rs (also known as T2Rs)),
which represent a distinct class of G-protein-coupled receptors. Among the 26 members of …
which represent a distinct class of G-protein-coupled receptors. Among the 26 members of …
A singular shark bitter taste receptor provides insights into the evolution of bitter taste perception
M Behrens, T Lang… - Proceedings of the …, 2023 - National Acad Sciences
Many animal and plant species synthesize toxic compounds as deterrent; thus, detection of
these compounds is of vital importance to avoid their ingestion. Often, such compounds are …
these compounds is of vital importance to avoid their ingestion. Often, such compounds are …
Relevance of Phytochemical Taste for Anti-Cancer Activity: A Statistical Inquiry
Targeting inflammation and the pathways linking inflammation with cancer is an innovative
therapeutic strategy. Tastants are potential candidates for this approach, since taste …
therapeutic strategy. Tastants are potential candidates for this approach, since taste …
A bitter-taste receptor activated in a surprising way
A Di Pizio - 2024 - nature.com
A bitter-taste receptor activated in a surprising way Skip to main content Thank you for visiting
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Bitter Phytochemicals as Novel Candidates for Skin Disease Treatment
TC Grădinaru, A Vlad, M Gilca - Current Issues in Molecular Biology, 2023 - mdpi.com
Skin diseases represent a global healthcare challenge due to their rising incidence and
substantial socio-economic burden. While biological, immunological, and targeted therapies …
substantial socio-economic burden. While biological, immunological, and targeted therapies …
Multi-omics analysis reveals a feedback loop amplifying immune responses in acute graft-versus-host disease due to imbalanced gut microbiota and bile acid …
L Han, X Sun, J Kong, J Li, K Feng, Y Bai… - Journal of Translational …, 2024 - Springer
Acute graft-versus-host disease (aGVHD) is primarily driven by allogeneic donor T cells
associated with an altered composition of the host gut microbiome and its metabolites. The …
associated with an altered composition of the host gut microbiome and its metabolites. The …
BitterMasS: Predicting Bitterness from Mass Spectra
Bitter compounds are common in nature and among drugs. Previously, machine learning
tools were developed to predict bitterness from the chemical structure. However, known …
tools were developed to predict bitterness from the chemical structure. However, known …
Influence of Sodium Chloride on Human Bitter Taste Receptor Responses
P Kumar, M Behrens - Journal of Agricultural and Food Chemistry, 2024 - ACS Publications
In the past, taste interactions between sodium chloride (NaCl) and bitter tastants were
investigated in human sensory studies, and the suppression of bitterness by sodium was …
investigated in human sensory studies, and the suppression of bitterness by sodium was …
The taste for health: the role of taste receptors and their ligands in the complex food/health relationship
G Morini - Frontiers in Nutrition, 2024 - frontiersin.org
Taste, food, and health are terms that have since always accompanied the act of eating, but
the association was simple: taste serves to classify a food as good or bad and therefore …
the association was simple: taste serves to classify a food as good or bad and therefore …