Seprase: an overview of an important matrix serine protease
P O'Brien, BF O'Connor - Biochimica et Biophysica Acta (BBA)-Proteins …, 2008 - Elsevier
Seprase or Fibroblast Activation Protein (FAP) is an integral membrane serine peptidase,
which has been shown to have gelatinase activity. Seprase has a dual function in tumour …
which has been shown to have gelatinase activity. Seprase has a dual function in tumour …
Multiple pathways of cell invasion are regulated by multiple families of serine proteases
The complex process of tumor invasion requires the coordinated expression and activity of
cell-substratum adhesive interactions and of cell-associated protease systems, which …
cell-substratum adhesive interactions and of cell-associated protease systems, which …
High‐throughput proteomic analysis of human infiltrating ductal carcinoma of the breast
RI Somiari, A Sullivan, S Russell, S Somiari, H Hu… - …, 2003 - Wiley Online Library
Large‐scale proteomics will play a critical role in the rapid display, identification and
validation of new protein targets, and elucidation of the underlying molecular events that are …
validation of new protein targets, and elucidation of the underlying molecular events that are …
Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1
H Neubauer, SE Clare, W Wozny, GP Schwall… - Breast Cancer …, 2008 - Springer
Introduction Breast tumors lacking the estrogen receptor-α (ER-α) have increased incidence
of resistance to therapy and poorer clinical prognosis. Methods Whole tissue sections from …
of resistance to therapy and poorer clinical prognosis. Methods Whole tissue sections from …
High preoperative plasma fibrinogen levels are associated with distant metastases and impaired prognosis after curative resection in patients with colorectal cancer
L Tang, K Liu, J Wang, C Wang… - Journal of surgical …, 2010 - Wiley Online Library
Background The purpose of this study was to evaluate the association between preoperative
plasma fibrinogen levels on clinicopathologic parameters and overall survival in patients …
plasma fibrinogen levels on clinicopathologic parameters and overall survival in patients …
Fibrinogen γ overexpression in pancreatic cancer identified by large-scale proteomic analysis of serum samples
M Bloomston, JX Zhou, AS Rosemurgy, W Frankel… - Cancer research, 2006 - AACR
Detection of serum markers for pancreatic cancer has been elusive. Although CA 19-9 is
most commonly used, its sensitivity and specificity are modest. We used large-scale …
most commonly used, its sensitivity and specificity are modest. We used large-scale …
[HTML][HTML] Accuracy of D-dimer/fibrinogen ratio to predict pulmonary embolism: a prospective diagnostic study
N Kucher, HP Kohler, T Dornhöfer, D Wallmann… - Journal of Thrombosis …, 2003 - Elsevier
Summary d-Dimer and fibrinogen are elevated in many diseases presenting signs and
symptoms similar to those seen in patients with pulmonary embolism (PE). We tested the …
symptoms similar to those seen in patients with pulmonary embolism (PE). We tested the …
[HTML][HTML] Prognostic significance of preoperative fibrinogen in patients with colon cancer
ZQ Sun, XN Han, HJ Wang, Y Tang… - World Journal of …, 2014 - ncbi.nlm.nih.gov
METHODS: A total of 255 colon cancer patients treated at the Affiliated Tumor Hospital of
Xinjiang Medical University from June 1 st 2005 to June 1 st 2008 were enrolled in the study …
Xinjiang Medical University from June 1 st 2005 to June 1 st 2008 were enrolled in the study …
Proteomics of breast carcinoma
RI Somiari, S Somiari, S Russell, CD Shriver - Journal of Chromatography B, 2005 - Elsevier
Beast cancer is the most diagnosed cancer in women, accounting for approximately 40,000
deaths annually in the USA. Significant advances have been made in the areas of detection …
deaths annually in the USA. Significant advances have been made in the areas of detection …
Concomitant determination of absolute values of cellular protein amounts, synthesis rates, and turnover rates by quantitative proteome profiling
C Gerner, S Vejda, D Gelbmann, E Bayer… - Molecular & Cellular …, 2002 - ASBMB
Two-dimensional gel electrophoresis of protein fractions isolated from 35 S-radiolabeled
cells provides qualitative information on intracellular amounts, 35 S incorporation rates …
cells provides qualitative information on intracellular amounts, 35 S incorporation rates …