Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity

N Shen, T Wang, Q Gan, S Liu, L Wang, B Jin - Food chemistry, 2022 - Elsevier
Flavonoids are a group of natural polyphenol substances abundant in vegetables, fruits,
grains, and tea. As plant secondary metabolites, flavonoids play essential roles in many …

Mechanisms of oxidized LDL-mediated endothelial dysfunction and its consequences for the development of atherosclerosis

H Jiang, Y Zhou, SM Nabavi, A Sahebkar… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is an immuno-metabolic disease involving chronic inflammation, oxidative
stress, epigenetics, and metabolic dysfunction. There is compelling evidence suggesting …

A two-pronged detection of atherosclerosis with a dual-channel fluorescent probe for viscosity and hypochlorous acid

Z Wang, S Wang, B Wang, J Shen, L Zhao, F Yu… - Chemical Engineering …, 2023 - Elsevier
The precise detection of atherosclerosis has been a research hot point since its importance
in the diagnosis of cardiovascular diseases. Here we synthesized a near-infrared …

Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Biochemistry of antioxidants: Mechanisms and pharmaceutical applications

S Losada-Barreiro, Z Sezgin-Bayindir, F Paiva-Martins… - Biomedicines, 2022 - mdpi.com
Natural antioxidants from fruits and vegetables, meats, eggs and fish protect cells from the
damage caused by free radicals. They are widely used to reduce food loss and waste …

Metformin, macrophage dysfunction and atherosclerosis

X Feng, W Chen, X Ni, PJ Little, S Xu, L Tang… - Frontiers in …, 2021 - frontiersin.org
Metformin is one of the most widely prescribed hypoglycemic drugs and has the potential to
treat many diseases. More and more evidence shows that metformin can regulate the …

Inflammation: A new look at an old problem

E Gusev, Y Zhuravleva - International Journal of Molecular Sciences, 2022 - mdpi.com
Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

[HTML][HTML] Tanshinone IIA protects human coronary artery endothelial cells from ferroptosis by activating the NRF2 pathway

L He, YY Liu, K Wang, C Li, W Zhang, ZZ Li… - Biochemical and …, 2021 - Elsevier
The pathogenesis of atherosclerosis is closely related to endothelial cell injury caused by
lipid peroxidation-induced ferroptosis. Tanshinone IIA (TSA) protects endothelial tissues …

Advance in the pharmacological effects of quercetin in modulating oxidative stress and inflammation related disorders

Y Zhou, C Qian, Y Tang, M Song, T Zhang… - Phytotherapy …, 2023 - Wiley Online Library
Numerous pharmacological effects of quercetin have been illustrated, including
antiinflammation, antioxidation, and anticancer properties. In recent years, the antioxidant …

Methyl benzoate derivatives: in vitro Paraoxonase 1 inhibition and in silico studies

IN Korkmaz, C Türkeş, Y Demir… - … of Biochemical and …, 2022 - Wiley Online Library
Abstract Paraoxonase 1 (PON1) can metabolize some compounds such as aromatic
carboxylic acid and unsaturated aliphatic esters, arylesters, cyclic carbonate, plucuronide …