[HTML][HTML] The sirtuin family in health and disease
QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
Naringenin: A potential flavonoid phytochemical for cancer therapy
Naringenin is an important phytochemical which belongs to the flavanone group of
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …
Post‐translational modifications of histones: Mechanisms, biological functions, and therapeutic targets
R Liu, J Wu, H Guo, W Yao, S Li, Y Lu, Y Jia… - MedComm, 2023 - Wiley Online Library
Histones are DNA‐binding basic proteins found in chromosomes. After the histone
translation, its amino tail undergoes various modifications, such as methylation, acetylation …
translation, its amino tail undergoes various modifications, such as methylation, acetylation …
The global burden of leukemia and its attributable factors in 204 countries and territories: findings from the global burden of disease 2019 study and projections to …
M Du, W Chen, K Liu, L Wang, Y Hu, Y Mao… - Journal of …, 2022 - Wiley Online Library
Background. Leukemia is a common malignancy that has four main subtypes and is a threat
to human health. Understanding the epidemiological status of leukemia and its four main …
to human health. Understanding the epidemiological status of leukemia and its four main …
[HTML][HTML] Etiology of acute leukemia: A review
CK Tebbi - Cancers, 2021 - mdpi.com
Simple Summary Acute leukemias are some of the most common cancers affecting all age
groups. Despite a significant improvement made in the treatment of acute leukemias, their …
groups. Despite a significant improvement made in the treatment of acute leukemias, their …
[HTML][HTML] Disease burden, risk factors, and trends of leukaemia: a global analysis
Leukaemia accounted for approximately 2.5% of all new cancer incidence and 3.1% of
cancer-related mortality. The investigation of its risk factors and epidemiologic trends could …
cancer-related mortality. The investigation of its risk factors and epidemiologic trends could …
[HTML][HTML] lncRNA PVT1: a novel oncogene in multiple cancers
R Li, X Wang, C Zhu, K Wang - Cellular & molecular biology letters, 2022 - Springer
Long noncoding RNAs are involved in epigenetic gene modification, including binding to the
chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in …
chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in …
[HTML][HTML] Melatonin as a regulator of apoptosis in leukaemia: molecular mechanism and therapeutic perspectives
A Mafi, H Rismanchi, Y Gholinezhad… - Frontiers in …, 2023 - frontiersin.org
Leukaemia is a dangerous malignancy that causes thousands of deaths every year
throughout the world. The rate of morbidity and mortality is significant despite many …
throughout the world. The rate of morbidity and mortality is significant despite many …
[HTML][HTML] Green metallic nanoparticles for cancer therapy: evaluation models and cancer applications
E Tinajero-Diaz, D Salado-Leza, C Gonzalez… - Pharmaceutics, 2021 - mdpi.com
Metal-based nanoparticles are widely used to deliver bioactive molecules and drugs to
improve cancer therapy. Several research works have highlighted the synthesis of gold and …
improve cancer therapy. Several research works have highlighted the synthesis of gold and …
Multifunctional targetable liposomal drug delivery system in the management of leukemia: Potential, opportunities, and emerging strategies
The concern impeding the success of chemotherapy in leukemia treatment is descending
efficacy of drugs because of multiple drug resistance (MDR). The previous failure of …
efficacy of drugs because of multiple drug resistance (MDR). The previous failure of …