[HTML][HTML] The sirtuin family in health and disease

QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Naringenin: A potential flavonoid phytochemical for cancer therapy

M Motallebi, M Bhia, HF Rajani, I Bhia, H Tabarraei… - Life Sciences, 2022 - Elsevier
Naringenin is an important phytochemical which belongs to the flavanone group of
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …

Post‐translational modifications of histones: Mechanisms, biological functions, and therapeutic targets

R Liu, J Wu, H Guo, W Yao, S Li, Y Lu, Y Jia… - MedComm, 2023 - Wiley Online Library
Histones are DNA‐binding basic proteins found in chromosomes. After the histone
translation, its amino tail undergoes various modifications, such as methylation, acetylation …

The global burden of leukemia and its attributable factors in 204 countries and territories: findings from the global burden of disease 2019 study and projections to …

M Du, W Chen, K Liu, L Wang, Y Hu, Y Mao… - Journal of …, 2022 - Wiley Online Library
Background. Leukemia is a common malignancy that has four main subtypes and is a threat
to human health. Understanding the epidemiological status of leukemia and its four main …

[HTML][HTML] Etiology of acute leukemia: A review

CK Tebbi - Cancers, 2021 - mdpi.com
Simple Summary Acute leukemias are some of the most common cancers affecting all age
groups. Despite a significant improvement made in the treatment of acute leukemias, their …

[HTML][HTML] Disease burden, risk factors, and trends of leukaemia: a global analysis

J Huang, SC Chan, CH Ngai, V Lok, L Zhang… - Frontiers in …, 2022 - frontiersin.org
Leukaemia accounted for approximately 2.5% of all new cancer incidence and 3.1% of
cancer-related mortality. The investigation of its risk factors and epidemiologic trends could …

[HTML][HTML] lncRNA PVT1: a novel oncogene in multiple cancers

R Li, X Wang, C Zhu, K Wang - Cellular & molecular biology letters, 2022 - Springer
Long noncoding RNAs are involved in epigenetic gene modification, including binding to the
chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in …

[HTML][HTML] Melatonin as a regulator of apoptosis in leukaemia: molecular mechanism and therapeutic perspectives

A Mafi, H Rismanchi, Y Gholinezhad… - Frontiers in …, 2023 - frontiersin.org
Leukaemia is a dangerous malignancy that causes thousands of deaths every year
throughout the world. The rate of morbidity and mortality is significant despite many …

[HTML][HTML] Green metallic nanoparticles for cancer therapy: evaluation models and cancer applications

E Tinajero-Diaz, D Salado-Leza, C Gonzalez… - Pharmaceutics, 2021 - mdpi.com
Metal-based nanoparticles are widely used to deliver bioactive molecules and drugs to
improve cancer therapy. Several research works have highlighted the synthesis of gold and …

Multifunctional targetable liposomal drug delivery system in the management of leukemia: Potential, opportunities, and emerging strategies

E Pardhi, R Yadav, A Chaurasiya, J Madan, SK Guru… - Life Sciences, 2023 - Elsevier
The concern impeding the success of chemotherapy in leukemia treatment is descending
efficacy of drugs because of multiple drug resistance (MDR). The previous failure of …