Antiviral strategies targeting host factors and mechanisms obliging+ ssRNA viral pathogens

S Mahajan, S Choudhary, P Kumar, S Tomar - Bioorganic & Medicinal …, 2021 - Elsevier
The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …

Administration of COVID-19 vaccines in immunocompromised patients

M Negahdaripour, M Shafiekhani, SMI Moezzi… - International …, 2021 - Elsevier
Since the beginning of vaccination programs against COVID-19 in different countries,
several populations such as patients with specific immunological conditions have been …

Marine sulfated polysaccharides as potential antiviral drug candidates to treat Corona Virus disease (COVID-19)

M Andrew, G Jayaraman - Carbohydrate Research, 2021 - Elsevier
The viral infection caused by SARS-CoV-2 has increased the mortality rate and engaged
several adverse effects on the affected individuals. Currently available antiviral drugs have …

Advances in research on antiviral activities of sulfated polysaccharides from seaweeds

Q Wei, G Fu, K Wang, Q Yang, J Zhao, Y Wang, K Ji… - Pharmaceuticals, 2022 - mdpi.com
In recent years, various viral diseases have suddenly erupted, resulting in widespread
infection and death. A variety of biological activities from marine natural products have …

[HTML][HTML] Potential of cell-penetrating peptides (CPPs) in delivery of antiviral therapeutics and vaccines

I Sadeghian, R Heidari, S Sadeghian, MJ Raee… - European Journal of …, 2022 - Elsevier
Viral infections are a great threat to human health. Currently, there are no effective vaccines
and antiviral drugs against the majority of viral diseases, suggesting the need to develop …

Analytical approaches for determination of COVID-19 candidate drugs in human biological matrices

R Mahdavi, Z Talebpour - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Since the outbreak of the COVID-19 pandemic, the use of antiviral and other available drugs
has been considered to combat or reduce the clinical symptoms of patients. In this regard, it …

Engineered nanoscale lipid-based formulation as potential enhancer of gefitinib lymphatic delivery: cytotoxicity and apoptotic studies against the A549 cell line

AY Sherif, GI Harisa, FK Alanazi, FA Nasr… - AAPS …, 2022 - Springer
The present study aimed to engineer a nanoscale lipid-based lymphatic drug delivery
system with D-α-Tocopherol polyethylene glycol 1000 succinate to combat the lymphatic …

Drug-based therapeutic strategies for COVID-19-infected patients and their challenges

K Zarkesh, E Entezar-Almahdi, P Ghasemiyeh… - Future …, 2021 - Taylor & Francis
Emerging epidemic-prone diseases have introduced numerous health and economic
challenges in recent years. Given current knowledge of COVID-19, herd immunity through …

Infection of human cells by SARS-CoV-2 and molecular overview of gastrointestinal, neurological, and hepatic problems in COVID-19 patients

M Rahban, A Stanek, A Hooshmand… - Journal of Clinical …, 2021 - mdpi.com
The gastrointestinal tract is the body's largest interface between the host and the external
environment. People infected with SARS-CoV-2 are at higher risk of microbiome alterations …

A multidisciplinary approach to coronavirus disease (COVID-19)

A Gediz Erturk, A Sahin, E Bati Ay, E Pelit, E Bagdatli… - Molecules, 2021 - mdpi.com
Since December 2019, humanity has faced an important global threat. Many studies have
been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus …