Osteoarthritis (OA) is a degenerative joint disease characterized by low-grade inflammation
and high levels of clinical heterogeneity. Aberrant chondrocyte metabolism is a response to …

This year in review on osteoarthritis biology summarizes a series of research articles
published between the 2020 and 2021 Osteoarthritis Research Society International …

Insufficient intracellular anabolism is a crucial factor involved in many pathological
processes in the body,. The anabolism of intracellular substances requires the consumption …

MicroRNAs (miRNAs) regulate several physiological and pathological processes involved in
various diseases, including osteoarthritis (OA). OA is the most common global …

Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

Reactive oxygen species (ROS) plays a critical role in tissue repair, including bone.
Therefore, detecting and regulating ROS is essential for monitoring and facilitating bone …

Cartilage-targeting delivery of therapeutic agents is still an effective strategy for osteoarthritis
(OA) therapy. Recently, scavenging for reactive oxygen species (ROS) and activating …

Clinically, intra-articular administration can hardly achieve the truly targeted therapy, and the
drugs are usually insufficient to show local and long-term therapeutic effects because of their …

Osteoarthritis (OA) is a chronic joint disease characterized by progressive degeneration of
articular cartilage. A challenge in the development of disease-modifying drugs is effective …

Osteoporosis is caused by an osteoclast activation mechanism. People suffering from
osteoporosis are prone to bone defects. Increasing evidence indicates that scavenging …