An in-silico analysis of ivermectin interaction with potential SARS-CoV-2 targets and host nuclear importin α

F Azam, IM Taban, EEM Eid, M Iqbal… - Journal of …, 2022 - Taylor & Francis
Ivermectin (IVM) is a broad-spectrum antiparasitic agent, having inhibitory potential against
wide range of viral infections. It has also been found to hamper SARS-CoV-2 replication in …

[HTML][HTML] RETRACTED ARTICLE: Multifaceted role of natural sources for COVID-19 pandemic as marine drugs

MM Rahman, MR Islam, S Shohag, ME Hossain… - … Science and Pollution …, 2022 - Springer
COVID-19, which is caused by the novel severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has quickly spread over the world, posing a global health concern. The …

[HTML][HTML] Predicting the effects of rare genetic variants on oncogenic signaling pathways: A computational analysis of HRAS protein function

S Ali, U Ali, A Qamar, I Zafar, M Yaqoob, Q Ain… - Frontiers in …, 2023 - frontiersin.org
The HRAS gene plays a crucial role in regulating essential cellular processes for life, and
this gene's misregulation is linked to the development of various types of cancers …

[HTML][HTML] Spectroscopic details on the molecular structure of pyrimidine‑2‑thiones heterocyclic compounds: computational and antiviral activity against the main …

DSE Sayed, ESM Abdelrehim - BMC chemistry, 2022 - Springer
Computational tools in investigating of spectral heterocyclic compounds ranges based on
pyrimidine‑2‑thiones, take some importance in identifying their molecular and electronic …

[HTML][HTML] The anti-viral applications of marine resources for COVID-19 treatment: an overview

S Geahchan, H Ehrlich, MA Rahman - Marine Drugs, 2021 - mdpi.com
The ongoing pandemic has led to an urgent need for novel drug discovery and potential
therapeutics for Sars-CoV-2 infected patients. Although Remdesivir and the anti …

[HTML][HTML] Computational simulations identified marine-derived natural bioactive compounds as replication inhibitors of SARS-CoV-2

V Kumar, S Parate, S Yoon, G Lee… - Frontiers in microbiology, 2021 - frontiersin.org
The rapid spread of COVID-19, caused by the novel severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a worldwide health emergency. Unfortunately, to date, a …

[HTML][HTML] Identification of lactoferrin-derived peptides as potential inhibitors against the main protease of SARS-CoV-2

W Zhao, X Li, Z Yu, S Wu, L Ding, J Liu - LWT, 2022 - Elsevier
COVID-19 is a global health emergency that causes serious concerns. A global effort is
underway to identify drugs for the treatment of COVID-19. One possible solution to the …

[HTML][HTML] Important roles of oligo-and polysaccharides against SARS-CoV-2: recent advances

S Iravani, RS Varma - Applied Sciences, 2021 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-initiated outbreak of
COVID-19 has spread rapidly around the world, posing a huge threat to public health …

[HTML][HTML] A computer-aided drug design approach to predict marine drug-like leads for SARS-CoV-2 main protease inhibition

SP Gaudêncio, F Pereira - Marine drugs, 2020 - mdpi.com
The investigation of marine natural products (MNPs) as key resources for the discovery of
drugs to mitigate the COVID-19 pandemic is a developing field. In this work, computer-aided …

Novel Drug Design for Treatment of COVID‐19: A Systematic Review of Preclinical Studies

S Mousavi, S Zare, M Mirzaei… - Canadian Journal of …, 2022 - Wiley Online Library
Background. Since the beginning of the novel coronavirus (SARS‐CoV‐2) disease
outbreak, there has been an increasing interest in discovering potential therapeutic agents …