[HTML][HTML] Exploring the therapeutic potential of marine-derived bioactive compounds against COVID-19

R Singh, N Chauhan, M Kuddus - Environmental Science and Pollution …, 2021 - Springer
The ocean is the most biodiverse habitat of various organisms. The organisms surviving in
the harsh conditions of the ocean consist of several spectacular properties and produce …

Lactobacillus casei-derived postbiotics inhibited digestion of triglycerides, glycerol phospholipids and sterol lipids via allosteric regulation of BSSL, PTL and PLA2 to …

Z Fan, W Jia - Food & Function, 2023 - pubs.rsc.org
The anti-obesity potential of probiotics has been widely reported, however their utilization in
high-risk patients and potential adverse reactions have led researchers to focus their …

[HTML][HTML] Emerging mutations in envelope protein of SARS-CoV-2 and their effect on thermodynamic properties

K Mou, M Abdalla, DQ Wei, MT Khan, MS Lodhi… - Informatics in medicine …, 2021 - Elsevier
Structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are
potential drug targets due to their role in the virus life cycle. The envelope (E) protein is one …

[HTML][HTML] Emerging mutations in Nsp1 of SARS-CoV-2 and their effect on the structural stability

K Mou, F Mukhtar, MT Khan, DB Darwish, S Peng… - Pathogens, 2021 - mdpi.com
The genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes 16
non-structural (Nsp) and 4 structural proteins. Among the Nsps, Nsp1 inhibits host gene …

[HTML][HTML] Biologically active compounds from marine organisms in the strategies for combating coronaviruses

TS Zaporozhets, NN Besednova - AIMS microbiology, 2020 - ncbi.nlm.nih.gov
Despite the progress made in immunization and drug development, so far there are no
prophylactic vaccines and effective therapies for many viral infections, including infections …

Computer‐Aided Analysis of Multiple SARS‐CoV‐2 Therapeutic Targets: Identification of Potent Molecules from African Medicinal Plants

FN Iheagwam, SO Rotimi - Scientifica, 2020 - Wiley Online Library
The COVID‐19 pandemic, which started in Wuhan, China, has spread rapidly over the world
with no known antiviral therapy or vaccine. Interestingly, traditional Chinese medicine …

[HTML][HTML] Recent progresses in marine microbial-derived antiviral natural products

YF Teng, L Xu, MY Wei, CY Wang, YC Gu… - Archives of Pharmacal …, 2020 - Springer
Viruses have always been a class of pathogenic microorganisms that threaten the health
and safety of human life worldwide. However, for a long time, the treatment of viral infections …

Identification of Berbamine, Oxyacanthine and Rutin from Berberis asiatica as anti-SARS-CoV-2 compounds: An in silico study

T Joshi, S Bhat, H Pundir, S Chandra - Journal of Molecular Graphics and …, 2021 - Elsevier
Owing to the shortage of specific medicines, the global pandemic of COVID-19 caused by
SARS-CoV-2 has been the greatest challenge for the science community. Researchers from …

Protein reliability analysis and virtual screening of natural inhibitors for SARS-CoV-2 main protease (Mpro) through docking, molecular mechanic & dynamic, and …

K Kapusta, S Kar, JT Collins, LM Franklin… - Journal of …, 2021 - Taylor & Francis
Due to an outbreak of COVID-19, the number of research papers devoted to in-silico drug
discovery of potential antiviral drugs is increasing every day exponentially. Still, there is no …

[HTML][HTML] Marine sponge is a promising natural source of anti-SARS-CoV-2 scaffold

AM Hamoda, B Fayed, NS Ashmawy… - Frontiers in …, 2021 - frontiersin.org
The current pandemic caused by SARS-CoV2 and named COVID-19 urgent the need for
novel lead antiviral drugs. Recently, United States Food and Drug Administration (FDA) …