[HTML][HTML] The potential role of ferroptosis in COVID-19-related cardiovascular injury

L Yang, Y Wu, W Jin, N Mo, G Ye, Z Su, L Tang… - Biomedicine & …, 2023 - Elsevier
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
emerged as a global health threat in 2019. An important feature of the disease is that …

[HTML][HTML] The role of ferroptosis in virus infections

J Wang, J Zhu, S Ren, Z Zhang, K Niu, H Li… - Frontiers in …, 2023 - frontiersin.org
Regulated cell death (RCD) is a strategy employed by host cells to defend invasions of
pathogens, such as viruses and bacteria. Ferroptosis is a type of RCD characterized by …

[HTML][HTML] Fatal COVID-19 pulmonary disease involves ferroptosis

B Qiu, F Zandkarimi, A Saqi, C Castagna, H Tan… - Nature …, 2024 - nature.com
SARS-CoV-2 infection causes severe pulmonary manifestations, with poorly understood
mechanisms and limited treatment options. Hyperferritinemia and disrupted lung iron …

[HTML][HTML] Rotavirus-induced lncRNA SLC7A11-AS1 promotes ferroptosis by targeting cystine/glutamate antiporter xCT (SLC7A11) to facilitate virus infection

S Banerjee, R Sarkar, A Mukherjee, S Mitra, A Gope… - Virus Research, 2024 - Elsevier
Rotavirus (RV) is the primary etiological agent of virus-associated gastroenteritis in infants,
causing 200,000 childhood death annually. Despite the availability of vaccines, rotaviral …

[HTML][HTML] The Role of the NRF2 Pathway in the Pathogenesis of Viral Respiratory Infections

M Daskou, L Fotooh Abadi, C Gain, M Wong, E Sharma… - Pathogens, 2024 - mdpi.com
In humans, acute and chronic respiratory infections caused by viruses are associated with
considerable morbidity and mortality. Respiratory viruses infect airway epithelial cells and …

NRF2-mediated regulation of lipid pathways in viral infection

K Muzammil, ZS Ghnim, IS Gataa… - Molecular Aspects of …, 2024 - Elsevier
The first line of defense against viral infection of the host cell is the cellular lipid membrane,
which is also a crucial first site of contact for viruses. Lipids may sometimes be used as viral …

[HTML][HTML] SARS-CoV-2 Accessory Protein Orf7b Induces Lung Injury via c-Myc Mediated Apoptosis and Ferroptosis

R Deshpande, W Li, T Li, KV Fanning… - International Journal of …, 2024 - mdpi.com
The pandemic of coronavirus disease 2019 (COVID-19) has been the foremost modern
global public health challenge. The airway is the primary target in severe acute respiratory …

[HTML][HTML] Ferroptosis in cardiovascular diseases: role and mechanism

Q Zhang, Y Luo, L Peng, X Rong, Y Liu, J Li, J Luo - Cell & Bioscience, 2023 - Springer
In multicellular organisms, regulatory cell death is a crucial aspect of growth and
development. Ferroptosis, which was postulated roughly ten years ago, is a mode of cell …

[HTML][HTML] A deep insight into ferroptosis in lung disease: facts and perspectives

F Zhang, Y Xiang, Q Ma, E Guo, X Zeng - Frontiers in Oncology, 2024 - frontiersin.org
In the last decade, ferroptosis has received much attention from the scientific research
community. It differs from other modes of cell death at the morphological, biochemical, and …

Ferroptosis in viral infection: a potential therapeutic target

L Ding - Future Microbiology, 2024 - Taylor & Francis
Ferroptosis, known as a type of programmed cell death that is iron dependent, is
characterized by intracellular iron accumulation, glutathione depletion, glutathione …