PKC‐ε‐dependent cytosol‐to‐membrane translocation of pendrin in rat thyroid PC Cl3 cells

A Muscella, S Marsigliante, T Verri… - Journal of cellular …, 2008 - Wiley Online Library
We studied the expression and the hormonal regulation of the PDS gene product, pendrin,
which is, in thyrocytes, responsible for the iodide transport out of the cell. We show that PC …

[HTML][HTML] Methoprene-tolerant 1 regulates gene transcription to maintain insect larval status

WL Zhao, CY Liu, W Liu, D Wang… - Journal of Molecular …, 2014 - jme.bioscientifica.com
Polycystic ovary syndrome (PCOS) affects up to 18% of reproductive-aged women with
reproductive and metabolic complications. While lipidomics can identify associations …

Analysis of cellular localization and function of carboxy-terminal mutants of pendrin

A Bizhanova, TL Chew, S Khuon, P Kopp - Cellular Physiology and …, 2011 - karger.com
Background: Iodide uptake at the basolateral membrane and iodide efflux at the apical
membrane of thyrocytes, essential steps in the biosynthesis of thyroid hormone, are …

Intronic variants of SLC26A4 gene enhance splicing efficiency in hybrid minigene assay

R Kallel-Bouattour, S Belguith-Maalej, E Zouari-Bradai… - Gene, 2017 - Elsevier
The SLC26A4 genomic sequence screening in autoimmune thyroid diseases (AITD)
revealed different variants types with possible pathogenic effects. Although intronic variants …

[HTML][HTML] Interleukin-mediated pendrin transcriptional regulation in airway and esophageal epithelia

S Vanoni, G Scantamburlo, S Dossena… - International Journal of …, 2019 - mdpi.com
Pendrin (SLC26A4), a Cl−/anion exchanger, is expressed at high levels in kidney, thyroid,
and inner ear epithelia, where it has an essential role in bicarbonate secretion/chloride …

Active Hydrogen Free, Z-Isomer Selective Isatin Derived “Turn on” Fluorescent Dual Anions Sensor

M Shenbagapushpam, BCMA Ashwin… - Journal of …, 2024 - Springer
An efficient and anions fluorescence “on–off” sensor of 1-(prop-2-yn-1-yl)-3-(quinolin-3-
ylimino) indolin-2-one (PQI) has been developed for the selective sensing of dual anions of …

[HTML][HTML] Molecular Features of SLC26A4 Common Variant p. L117F

A Matulevičius, E Bernardinelli, Z Brownstein… - Journal of Clinical …, 2022 - mdpi.com
The SLC26A4 gene, which encodes the anion exchanger pendrin, is involved in
determining syndromic (Pendred syndrome) and non-syndromic (DFNB4) autosomal …

The pendrin polypeptide

S Dossena, E Bernardinelli, AK Sharma… - The Role of Pendrin in …, 2017 - Springer
Abstract Pendrin (SLC26A4) is an electroneutral anion exchanger in which function-altering
mutations cause inherited forms of non-syndromic (DFNB4) and syndromic deafness …

[HTML][HTML] SLC26A4 gene copy number variations in Chinese patients with non-syndromic enlarged vestibular aqueduct

J Zhao, Y Yuan, J Chen, S Huang, G Wang… - Journal of Translational …, 2012 - Springer
Background Many patients with enlarged vestibular aqueduct (EVA) have either only one
allelic mutant of the SLC26A4 gene or lack any detectable mutation. In this study, multiplex …

[HTML][HTML] The human pendrin promoter contains two N4 GAS motifs with different functional relevance

S Vanoni, C Nofziger, S Dossena, SM Soyal… - Cellular physiology and …, 2013 - karger.com
Background: Pendrin, an anion exchanger associated with the inner ear, thyroid and kidney,
plays a significant role in respiratory tissues and diseases, where its expression is increased …