Mesenchymal stem cells are culture-derived mesodermal progenitors isolatable from all
vascularized tissues. In spite of multiple fundamental, pre-clinical and clinical studies, the …

Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and asthma,
are one of the most frequent causes of morbidity and mortality in the global. COPD is …

Background: A comprehensive approach to the evaluation of biologic therapies for
musculoskeletal conditions is required to guide appropriate future use. Clinical studies …

BACKGROUND Correct development of the placenta is critical to establishing pregnancy
and inadequate placentation leads to implantation failure and miscarriage, as well as later …

ABSTRACT Human Mesenchymal Stem Cells, hMSCs, were first named over 25 years ago
with the “stem cell” nomenclature derived from the fact that we and others could cause these …

Autologous adipose tissue is used for tissue repletion and/or regeneration as an intact
lipoaspirate or as enzymatically derived stromal vascular fraction (SVF), which may be first …

The therapeutic benefits of exogenously delivered mesenchymal stromal/stem cells (MSCs)
have been largely attributed to their secretory properties. However, clinical translation of …

In the dense circulatory system of the kidney, as in all vascularized tissues, pericytes enwrap
capillaries and microvessels to regulate angiogenesis, stabilize microvascular networks and …

Mesenchymal stem/stromal cells (MSCs) are becoming increasingly important for the
development of cell therapeutics in regenerative medicine. Featuring immunomodulatory …

Biologic therapies, including stem cells, platelet-rich plasma, growth factors, and other
biologically active adjuncts, have recently received increased attention in the basic science …