The biological basis and prevention of preterm birth

GC Di Renzo, V Tosto, I Giardina - Best Practice & Research Clinical …, 2018 - Elsevier
The time of birth is a critical determinant of perinatal and long-term outcomes. Preterm birth
is still the first cause of infant mortality and morbidity; unfortunately, rates of preterm birth …

Management of clinical chorioamnionitis: an evidence-based approach

A Conde-Agudelo, R Romero, EJ Jung… - American journal of …, 2020 - Elsevier
This review aimed to examine the existing evidence about interventions proposed for the
treatment of clinical chorioamnionitis, with the goal of developing an evidence-based …

Preterm labor and birth management: recommendations from the European Association of Perinatal Medicine

GC Di Renzo, L Cabero Roura… - The Journal of …, 2017 - Taylor & Francis
GC Di Renzo a, L. Cabero Roura b, F. Facchinetti c, H. Helmer d, C. Hubinont e, B.
Jacobsson f, JS Jørgensen g, RF Lamont h, i, A. Mikhailov j, N. Papantoniou k, V. Radzinsky …

Antibiotic administration reduces the rate of intraamniotic inflammation in preterm prelabor rupture of the membranes

M Kacerovsky, R Romero, M Stepan, J Stranik… - American journal of …, 2020 - Elsevier
Background Preterm prelabor rupture of the membranes (PPROM) is frequently complicated
by intraamniotic inflammatory processes such as intraamniotic infection and sterile …

The human Ureaplasma species as causative agents of chorioamnionitis

EL Sweeney, SJ Dando, SG Kallapur… - Clinical microbiology …, 2017 - Am Soc Microbiol
The human Ureaplasma species are the most frequently isolated microorganisms from the
amniotic fluid and placentae of women who deliver preterm and are also associated with …

[HTML][HTML] Microplastics and additives in patients with preterm birth: The first evidence of their presence in both human amniotic fluid and placenta

J Halfar, K Čabanová, K Vávra, P Delongová, O Motyka… - Chemosphere, 2023 - Elsevier
Considering the well documented, almost ubiquitous nature of microplastics in different
environments, the exposure of pregnant women to microplastics may pose risks to the …

Comparison of rapid MMP-8 and interleukin-6 point-of-care tests to identify intra-amniotic inflammation/infection and impending preterm delivery in patients with …

P Chaemsaithong, R Romero, N Docheva… - The journal of …, 2018 - Taylor & Francis
Objective: Among patients presenting with preterm labor and intact membranes, those with
intra-amniotic inflammation have adverse obstetrical and neonatal outcomes. The diagnosis …

CXCL 10 and IL‐6: Markers of two different forms of intra‐amniotic inflammation in preterm labor

R Romero, P Chaemsaithong… - American journal of …, 2017 - Wiley Online Library
Problem To determine whether amniotic fluid (AF) CXCL 10 concentration is associated with
histologic chronic chorioamnionitis in patients with preterm labor (PTL) and preterm prelabor …

Cytokines in noninvasively obtained amniotic fluid as predictors of fetal inflammatory response syndrome

M Kunze, M Klar, CA Morfeld, B Thorns… - American journal of …, 2016 - Elsevier
Background In patients with preterm premature rupture of membranes, intrauterine
inflammation and/or infection is frequently present, can lead to fetal inflammatory response …

Cellular immune responses in amniotic fluid of women with preterm prelabor rupture of membranes

J Galaz, R Romero, R Slutsky, Y Xu… - Journal of perinatal …, 2020 - degruyter.com
Background Preterm birth is the leading cause of perinatal morbidity and mortality. Preterm
prelabor rupture of membranes (pPROM) occurs in 30% of preterm births; thus, this …