Current trends in polymer microneedle for transdermal drug delivery

KAS Al-Japairai, S Mahmood, SH Almurisi… - International journal of …, 2020 - Elsevier
Transdermal drug delivery using microneedles is increasingly gaining interest due to the
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …

[HTML][HTML] Matrix metalloproteinases: the sculptors of chronic cutaneous wounds

VR Krishnaswamy, D Mintz, I Sagi - Biochimica et Biophysica Acta (BBA) …, 2017 - Elsevier
Cutaneous wound healing is a complex mechanism with multiple processes orchestrating
harmoniously for structural and functional restoration of the damaged tissue. Chronic non …

3D printing as a technological strategy for the personalized treatment of wound healing

DT Uchida, ML Bruschi - AAPS PharmSciTech, 2023 - Springer
Wound healing is a dynamic process which involves stages of hemostasis, inflammation,
proliferation and remodeling. Any error in this process results in abnormal wound healing …

Animal tissue-derived biomaterials for promoting wound healing

X Cao, X Lin, N Li, X Zhao, M Zhou, Y Zhao - Materials Horizons, 2023 - pubs.rsc.org
The skin serves as the primary barrier between the human body and external environment,
and is therefore susceptible to damage from various factors. In response to this challenge …

Drug delivery with dissolving microneedles: Skin puncture, its influencing factors and improvement strategies

X Xiu, G Gao, Y Liu, F Ma - Journal of Drug Delivery Science and …, 2022 - Elsevier
Over the past decades, the use of microneedles, a unique transdermal drug delivery
technology, to deliver drugs to the skin for biological effects has been very active, and the …

[HTML][HTML] Engineered microneedles arrays for wound healing

S Yao, Y Luo, Y Wang - Engineered Regeneration, 2022 - Elsevier
Wound healing is the regenerative process of original skin structure after destructing by
different damage sources. Due to their transdermal delivery capability and high specific …

[HTML][HTML] Microneedles for enhanced topical treatment of skin disorders: applications, challenges, and prospects

T Peng, Y Chen, W Hu, Y Huang, M Zhang, C Lu… - Engineering, 2023 - Elsevier
Microneedles (MNs) can be used for the topical treatment of skin disorders as they directly
deliver therapeutics to the site of skin lesions, resulting in increased therapeutic efficacy …

Customized flexible hollow microneedles for psoriasis treatment with reduced‐dose drug

Y Ren, J Li, Y Chen, J Wang, Y Chen… - Bioengineering & …, 2023 - Wiley Online Library
Microneedles, especially hollow microneedles (HMNs), play an important role in drug
delivery, but most of the current HMNs are manufactured based on silicon microfabrication …

Three-dimensional (3D) printed microneedles for microencapsulated cell extrusion

C Farias, R Lyman, C Hemingway, H Chau, A Mahacek… - Bioengineering, 2018 - mdpi.com
Cell-hydrogel based therapies offer great promise for wound healing. The specific aim of this
study was to assess the viability of human hepatocellular carcinoma (HepG2) cells …

Nanobiomaterials: from 0D to 3D for tumor therapy and tissue regeneration

Y Liu, Q Yu, J Chang, C Wu - Nanoscale, 2019 - pubs.rsc.org
Nanobiomaterials have attracted tremendous attention in the biomedical field. Especially in
the past few years, a large number of low dimensional nanobiomaterials, including 0D …