Mesenchymal stem cell-derived exosomes: applications in regenerative medicine
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …
are then released into the extracellular space through a merging of the multivesicular body …
Exosomes from adipose‐derived stem cells and application to skin wound healing
Y An, S Lin, X Tan, S Zhu, F Nie, Y Zhen, L Gu… - Cell …, 2021 - Wiley Online Library
Skin wound healing is an intractable problem that represents an urgent clinical need. To
solve this problem, a large number of studies have focused on the use of exosomes (EXOs) …
solve this problem, a large number of studies have focused on the use of exosomes (EXOs) …
GelMA/PEGDA microneedles patch loaded with HUVECs-derived exosomes and Tazarotene promote diabetic wound healing
Clinical work and research on diabetic wound repair remain challenging globally. Although
various conventional wound dressings have been continuously developed, the efficacy is …
various conventional wound dressings have been continuously developed, the efficacy is …
Clinical applications of stem cell-derived exosomes
F Tan, X Li, Z Wang, J Li, K Shahzad… - Signal Transduction and …, 2024 - nature.com
Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …
certain diseases more successfully than conventional surgery, it nevertheless comes with …
Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration
DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …
Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
C Zhou, B Zhang, Y Yang, Q Jiang, T Li, J Gong… - Stem cell research & …, 2023 - Springer
Wound healing is a dynamic and highly sequential process involving a series of overlapping
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …
Efficient angiogenesis-based diabetic wound healing/skin reconstruction through bioactive antibacterial adhesive ultraviolet shielding nanodressing with exosome …
M Wang, C Wang, M Chen, Y Xi, W Cheng, C Mao… - ACS …, 2019 - ACS Publications
Diabetic wound healing and angiogenesis remain a worldwide challenge for both clinic and
research. The use of adipose stromal cell derived exosomes delivered by bioactive dressing …
research. The use of adipose stromal cell derived exosomes delivered by bioactive dressing …
Exosome‐guided phenotypic switch of M1 to M2 macrophages for cutaneous wound healing
Macrophages (Mϕs) critically contribute to wound healing by coordinating inflammatory,
proliferative, and angiogenic processes. A proper switch from proinflammatory M1 to anti …
proliferative, and angiogenic processes. A proper switch from proinflammatory M1 to anti …
Hopes and limits of adipose-derived stem cells (ADSCs) and mesenchymal stem cells (MSCs) in wound healing
Adipose tissue derived stem cells (ADSCs) are mesenchymal stem cells identified within
subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal …
subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal …
Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice
J Sanz-Ros, N Romero-García, C Mas-Bargues… - Science …, 2022 - science.org
Aging is associated with an increased risk of frailty, disability, and mortality. Strategies to
delay the degenerative changes associated with aging and frailty are particularly interesting …
delay the degenerative changes associated with aging and frailty are particularly interesting …