JAK/STAT3 signaling in cardiac fibrosis: a promising therapeutic target

H Jiang, J Yang, T Li, X Wang, Z Fan, Q Ye… - Frontiers in …, 2024 - frontiersin.org
Cardiac fibrosis is a serious health problem because it is a common pathological change in
almost all forms of cardiovascular diseases. Cardiac fibrosis is characterized by the …

Lnc-PXMP4-2-4 alleviates myocardial cell damage by activating the JAK2/STAT3 signaling pathway

H Zhang, Q Guo, G Feng, X Shen, X Feng, Y Guo… - Heliyon, 2023 - cell.com
Purpose The aim of this study was to investigate the protective effect of long non-coding lnc-
PXMP4-2-4 on myocardial cell damage caused by acute myocardial infarction (AMI) …

Exploring the role and mechanism of hyperoside against cardiomyocyte injury in mice with myocardial infarction based on JAK2/STAT3 signaling pathway

T Rao, H Tong, J Li, J Huang, Y Yin, J Zhang - Phytomedicine, 2024 - Elsevier
Background Myocardial infarction (MI) is one of the most deadly diseases in the world.
Hyperoside (Hyp) has been shown to have a protective effect on cardiovascular function …

SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental …

Y Yan, N Yuan, Y Chen, Y Ma, A Chen, F Wang… - Chinese Medicine, 2024 - Springer
Background Diabetic kidney disease (DKD) represents a microvascular complication of
diabetes mellitus. Shenkang Pills (SKP), a traditional Chinese medicine formula, has been …

Myricetin Restores Autophagy to Attenuate Lumbar Intervertebral Disk Degeneration Via Negative Regulation of the JAK2/STAT3 Pathway

T Mao, J Fan - Biochemical Genetics, 2024 - Springer
Autophagy is a critical player in lumbar intervertebral disk degeneration (IDD), and
autophagy activation has been suggested to prevent the apoptosis of nucleus pulposus cells …

An Expansion of the Endoplasmic Reticulum that Halts Autophagy is Permissive to Genome Instability

E Lara-Barba, A Torán-Vilarrubias… - …, 2023 - journals.sagepub.com
The links between autophagy and genome stability, and whether they are important for
lifespan and health, are not fully understood. We undertook a study to explore this notion at …

Identification of potential blood biomarkers of coronary artery disease using a cuproptosis gene set

J Li, B Xiang, Y Chen, Y Yin, C Fang, K Lei, Z Zhu… - 2023 - researchsquare.com
Background Coronary artery disease (CAD) is a multifactorial cardiovascular disease that
causes high mortality worldwide. Cuproptosis is a newly discovered method of programmed …

[图书][B] Nutritional Iron in Toxoplasma gondii Pathogenesis: Parasite Theft of Host Iron Machinery and the Requirement of Iron in the Host Immune Response

SL Denton - 2023 - search.proquest.com
Toxoplasma gondii is responsible for incurable parasitic infections on a global scale. All of
parasite nutrient acquisition occurs from the host environment, representing a focal point for …