Poor water solubility, off-target toxicity, and small therapeutic window are among major
obstacles for the development of drug products. Redox-responsive drug delivery …

The discovery of cisplatin followed by its success in anticancer therapy laid the foundation of
metal-based drug design and development. Further research led to discovery of other …

With the widespread global impact of cancer on humans and the extensive side effects
associated with current cancer treatments, a novel, effective, and safe treatment is needed …

After the serendipitous discovery of cisplatin, a platinum-based drug with chemotherapeutic
effects, an incredible amount of research in the area of coordination chemistry has been …

The appearance of new epidemic virus opened new questions on the treatment of viral
infections. The expectations in receiving answers and fast solutions from scientists are very …

Nucleoside analogues (NAs) are a family of compounds which include a variety of purine
and pyrimidine derivatives, widely used as anticancer and antiviral agents. For their ability to …

Decoding the interaction between coordination compounds and proteins is of fundamental
importance in biology, pharmacy, and medicine. In this context, protein–ligand docking …

The research goal is to determine whether platinum can be seen as a good investment. For
this purpose, content analysis of documents and deep learning neural networks with …

A series of mono and bimetallic ruthenium (II) arene complexes bearing diamine (Ru 1-6)
were prepared and fully characterized by 1 H, 13 C, 19 F, and 31 P NMR spectroscopy and …

Metal ions are the center of an important class of therapeutics, ie metallodrugs for their
unique coordination geometries and redox states. Many cellular functions depend on the …