Chronic obstructive pulmonary disease: epidemiology, biomarkers, and paving the way to lung cancer

K Szalontai, N Gémes, J Furák, T Varga… - Journal of clinical …, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD), the frequently fatal pathology of the
respiratory tract, accounts for half a billion cases globally. COPD manifests via chronic …

Aeroparticles, composition, and lung diseases

CI Falcon-Rodriguez, AR Osornio-Vargas… - Frontiers in …, 2016 - frontiersin.org
Urban air pollution is a serious worldwide problem due to its impact on human health. In the
past 60 years, growing evidence established a correlation between exposure to air …

Pathogenesis of chronic obstructive pulmonary disease

RM Tuder, I Petrache - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
The current epidemic of chronic obstructive pulmonary disease (COPD) has produced a
worldwide health care burden, approaching that imposed by transmittable infectious …

Stress-activated cap'n'collar transcription factors in aging and human disease

GP Sykiotis, D Bohmann - Science signaling, 2010 - science.org
Cap'n'collar (Cnc) transcription factors are conserved in metazoans and have important
developmental and homeostatic functions. The vertebrate Nrf1, Nrf2, and Nrf3; the …

Mechanisms of lung damage and development of COPD due to household biomass-smoke exposure: inflammation, oxidative stress, MicroRNAs, and gene …

B Ortiz-Quintero, I Martínez-Espinosa, R Pérez-Padilla - Cells, 2022 - mdpi.com
Chronic exposure to indoor biomass smoke from the combustion of solid organic fuels is a
major cause of disease burden worldwide. Almost 3 billion people use solid fuels such as …

Epidemiology of lung cancer

AG Schwartz, ML Cote - Lung cancer and personalized medicine: Current …, 2016 - Springer
Lung cancer continues to be one of the most common causes of cancer death despite
understanding the major cause of the disease: cigarette smoking. Smoking increases lung …

Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction

KF Chung, IM Adcock - European Respiratory Journal, 2008 - Eur Respiratory Soc
Chronic obstructive pulmonary disease is a leading global cause of morbidity and mortality
that is characterised by inexorable deterioration of small airways obstruction with …

The role of cigarette smoke-induced pulmonary vascular endothelial cell apoptosis in COPD

Q Song, P Chen, XM Liu - Respiratory Research, 2021 - Springer
Chronic obstructive pulmonary disease (COPD) is one of the most common chronic
respiratory diseases with high morbidity and mortality. It has become the fifth most burdened …

Alantolactone suppresses inflammation, apoptosis and oxidative stress in cigarette smoke-induced human bronchial epithelial cells through activation of Nrf2/HO-1 …

X Dang, B He, Q Ning, Y Liu, J Guo, G Niu… - Respiratory Research, 2020 - Springer
Background It is well established that airway remodeling and inflammation are
characteristics for chronic obstructive pulmonary disease (COPD). Moreover, cigarette …

[HTML][HTML] Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice

M Seimetz, N Parajuli, A Pichl, F Veit, G Kwapiszewska… - Cell, 2011 - cell.com
Chronic obstructive pulmonary disease (COPD) is one of the most common causes of death
worldwide. We report in an emphysema model of mice chronically exposed to tobacco …