Compromised limb blood flow in aging may contribute to the development of sarcopenia,
frailty, and the metabolic syndrome. We developed a novel contrast‐enhanced ultrasound …

In this review we discuss the contribution of NO, prostacyclin and endotheliumderived
relaxing factor—endothelium-derived hyperpolarizing factor, or EDHF, to vascular function …

The contribution of small-conductance (SKCa) and intermediate-conductance Ca2+-
activated K+ (IKCa) channels to the generation of nitric oxide (NO) by Ca2+-mobilizing …

Endothelial dysfunction plays a role in the development of atherosclerosis and diabetes‐
associated vascular disease and, in the streptozotocin (STZ)‐induced apoE‐deficient …

Four connexin (Cx) molecules, namely Cx37, Cx40, Cx43 and Cx45, are expressed in the
gap junctions that exist within and between the cellular layers of arteries. 2. Endothelial cells …

Endothelium plays a crucial role in the regulation of cardiovascular homeostasis through the
release of vasoactive factors. Besides nitric oxide (NO) and prostacyclin, increasing …

Aims Microdomain signalling mechanisms underlie key aspects of artery function and the
modulation of intracellular calcium, with transient receptor potential (TRP) channels playing …

Les points de vue sur le rôle des espèces oxygénées radicalaires (ROS) dans le système
vasculaire ont évolué au cours des dernières années; ainsi, les ROS ne sont plus …

It is well established that stimulation of receptors on the endothelium can elicit dilation of
arteries and arterioles by initiating the synthesis and release of nitric oxide (NO) and/or …

Vascular tone refers to the balance between arterial constrictor and dilator activity. The
mechanisms that underlie tone are critical for the control of haemodynamics and matching …