The principal mediators of vascular tone are neural, endothelial and physical stimuli that
result in the initiation of dilator and constrictor responses to facilitate the control of blood …

Insufficient hydrogen sulfide (H 2 S) has been implicated in Type 2 diabetic mellitus (T2DM)
and hyperhomocysteinemia (HHcy)-related cardiovascular complications. We investigated …

Glucocorticoid (GC)-induced hypertension is a common clinical problem still poorly
understood. The presence of GC receptor (GR) in vascular smooth muscle and endothelial …

Background The vascular endothelium plays a critical role in the control of blood flow.
Altered endothelium-mediated vasodilator and vasoconstrictor mechanisms underlie key …

[Frontiers in Bioscience S3, 946-960, June 1, 2011] 946 Endothelial dysfunction in hypertension:
The role of arginase Danielle L Page 1 [Frontiers in Bioscience S3, 946-960, June 1, 2011] 946 …

Bradykinin-induced relaxation of coronary microarteries: S-nitrosothiols as EDHF? - PMC Back
to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …

Cardiovascular diseases (CVD) such as myocardial infarction and stroke are a major cause
of morbidity and mortality worldwide. Impairment of the normal vasorelaxant functions of the …

Isosteviol is a derivative of stevioside, a constituent of Stevia rebaudiana, which is commonly
used as a noncaloric sugar substitute in Japan and Brazil. In the present study, the role of …

Myoendothelial microdomain signaling via localized calcium-activated potassium channel
(KCa) and gap junction connexins (Cx) is critical for endothelium-dependent vasodilation in …

A role for myoendothelial gap junctions (MEGJs) has been proposed in the action of the
vasodilator endothelium‐derived hyperpolarizing factor (EDHF). EDHF activity varies in …