miRNAs role in bladder cancer pathogenesis and targeted therapy: Signaling pathways interplay–A review
Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …
efforts have been exerted to improve BC patients' care. Besides, new approaches have …
Hallmarks and biomarkers of skin senescence: An updated review of skin senotherapeutics
D Bulbiankova, R Díaz-Puertas, FJ Álvarez-Martínez… - Antioxidants, 2023 - mdpi.com
Aging is a complex process characterized by an ongoing decline in physiological functions,
leading to degenerative diseases and an increased probability of death. Cellular …
leading to degenerative diseases and an increased probability of death. Cellular …
Explore the effect of the structure-activity relationship and dose-effect relationship on the antioxidant activity of licorice flavonoids
Y Hu, P Liang, Z Wang, CP Jiang, Q Zeng… - Journal of Molecular …, 2023 - Elsevier
Licorice flavonoids (LCF) are one of the homologous substances of medicine and food,
which have good antioxidant activity. However, the molecular mechanism affecting its …
which have good antioxidant activity. However, the molecular mechanism affecting its …
Mitochondrial aging and senolytic natural products with protective potential
A Deledda, E Giordano, F Velluzzi, G Flore… - International journal of …, 2022 - mdpi.com
Living organisms do not disregard the laws of thermodynamics and must therefore consume
energy for their survival. In this way, cellular energy exchanges, which aim above all at the …
energy for their survival. In this way, cellular energy exchanges, which aim above all at the …
Single-cell and spatial RNA sequencing reveal the spatiotemporal trajectories of fruit senescence
X Li, B Li, S Gu, X Pang, P Mason, J Yuan, J Jia… - Nature …, 2024 - nature.com
The senescence of fruit is a complex physiological process, with various cell types within the
pericarp, making it highly challenging to elucidate their individual roles in fruit senescence …
pericarp, making it highly challenging to elucidate their individual roles in fruit senescence …
Exosomal miR‐141‐3p from PDLSCs alleviates high glucose‐induced senescence of PDLSCs by activating the KEAP1‐NRF2 signaling pathway
M Liu, R Chen, Y Xu, J Zheng, M Wang… - Stem Cells …, 2023 - Wiley Online Library
Human periodontal ligament stem cells (PDLSCs) are the most promising stem cells for
periodontal tissue engineering. Senescent PDLSCs have diminished abilities to proliferate …
periodontal tissue engineering. Senescent PDLSCs have diminished abilities to proliferate …
[HTML][HTML] The redox-responsive roles of intermediate filaments in cellular stress detection, integration and mitigation
D Pérez-Sala, RA Quinlan - Current Opinion in Cell Biology, 2024 - Elsevier
Intermediate filaments are critical for cell and tissue homeostasis and for stress responses.
Cytoplasmic intermediate filaments form versatile and dynamic assemblies that interconnect …
Cytoplasmic intermediate filaments form versatile and dynamic assemblies that interconnect …
Crosstalk between oxidative stress and aging in neurodegeneration disorders
RF Abdelhamid, S Nagano - Cells, 2023 - mdpi.com
The world population is aging rapidly, and increasing lifespan exacerbates the burden of
age-related health issues. On the other hand, premature aging has begun to be a problem …
age-related health issues. On the other hand, premature aging has begun to be a problem …
Rational Design of Multifunctional Ferulic Acid Derivatives Aimed for Alzheimer's and Parkinson's Diseases
Ferulic acid has numerous beneficial effects on human health, which are frequently
attributed to its antioxidant behavior. In this report, many of them are reviewed, and 185 new …
attributed to its antioxidant behavior. In this report, many of them are reviewed, and 185 new …
Mitochondria pleiotropism in stem cell senescence: Mechanisms and therapeutic approaches
C Mas-Bargues - Free Radical Biology and Medicine, 2023 - Elsevier
Aging is a complex biological process characterized by a progressive decline in cellular and
tissue function, ultimately leading to organismal aging. Stem cells, with their regenerative …
tissue function, ultimately leading to organismal aging. Stem cells, with their regenerative …