Toll-like receptor 4 in bone marrow-derived cells as well as tissue-resident cells participate in aggravating autoimmune destructive arthritis

BT van den Brand, S Abdollahi-Roodsaz… - Annals of the …, 2013 - ard.bmj.com
Objective A prominent role of Toll-like receptor 4 (TLR4) in arthritis is emerging. TLR4 is
functional in immune cells and stromal cells. The aim was to investigate the involvement of …

Levels of interleukin 17, interleukin 23 and interleukin 27 in rheumatoid arthritis and osteoarthritis in Egyptian patients

AM Khalifa, HA Atia, S Saad - Al-Azhar Med J, 2013 - platform.almanhal.com
Background: Rheumatoid arthritis (RA) is a chronic systemic inflammatory autoimmune
disease associated with considerable disability, morbidity and mortality while osteoarthritis …

Engagement of CD14 Sensitizes Primary Monocytes to IFN-γ to Produce IL-12/23p40 and IL-23 Through p38 Mitogen-Activated Protein Kinase and Independent of …

MA Blahoianu, AAR Rahimi, N Gajanayaka… - Journal of Interferon & …, 2013 - liebertpub.com
Interferon (IFN)-γ is a potent stimulator of the IL-12 family Th1 cytokines, including IL-
12/23p40 and IL-23, responsible for coordinating the innate and adaptive immune …

Interleukin 23 and Interleukin 17 Evaluation Before and After Methotrexate Treatment of Basal Cell Carcinoma

N Said, S Khashaba, A Elgarf, D Esmat… - Zagazig University …, 2022 - journals.ekb.eg
Background: Interleukin 23 (IL 23) and Interleukin 17 (IL 17) are two vital cytokines
encountered in cutaneous and non-cutaneous immune-mediated inflammatory conditions …

[PDF][PDF] Effekte der Inhibition von Interleukin-12/23p40 versus TNF-α auf die Enthesitis bei Psoriasis Arthritis

CS Höpken - 2020 - opus4.kobv.de
Hintergrund und Ziele: Die Enthesitis ist vielfach Ursache von Schmerz,
Funktionseinschränkung und struktureller Gelenkzerstörung bei Patienten mit Psoriasis …

[图书][B] The role of IL-22 produced by Th17 cells in Type 1 Diabetes

SM Bellemore - 2013 - search.proquest.com
Abstract Interleukin-22 (IL-22) is produced by T helper 17 (Th17) cells. Th17 cells have been
shown to be pathogenic in autoimmune diseases, however their role in type 1 diabetes …

[PDF][PDF] Genetic variations in interleukin 12 related genes in autoimmune disease

RLJ van Wanrooij, A Zwiers, G Kraal… - IMMUNE-MEDIATED … - research.vu.nl
ABSTRACT The interleukin-12 (IL-12) family comprises a group of heterodimeric cytokines
and their respective receptors that play key roles in immune responses. A growing number …

The role of the cytokines IL-17A and IL-33 in inflammatory arthritis and psoriasis

AJ Hueber - 2011 - theses.gla.ac.uk
The inflammatory autoimmune diseases rheumatoid arthritis, psoriatic arthritis and psoriasis
have seen a break through in therapy by targeting cytokines in the last decade. Interleukin …

[图书][B] Genomic approaches for the identi cation of risk loci for Rheumatoid Arthritis

A Julià Cano - 2011 - ddd.uab.cat
Rheumatoid Arthritis (RA) is one of the most prevalent autoimmune diseases in the world
and is characterized by the chronic in ammation of the synovial joints. The origin of the …

[PDF][PDF] Some Methods for Solving Initial and Boundary Value Problems with nonlocal Conditions

JA Kahtan - 2013 - nahrainuniv.edu.iq
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic
inflammation and joint destruction. The aim of this study was to investigate some …