Abstract Interleukin-23 (IL-23) is a pro-inflammatory cytokine that was discovered in 2000. It
is part of the IL-12 family of cytokines which are also has IL-27 as a member. This group …

Th17 cells are critically involved in autoimmune disease induction and severity. Recently,
we showed that Th17 cells from patients with rheumatoid arthritis (RA) directly induced a …

In humans, several dendritic cell (DC) subsets have been identified, including the CD1c+
DCs, CD141+ DCs and plasmacytoid DC (pDC). It has been suggested that human CD141+ …

A artrite reumatoide (AR) é uma doença inflamatória, crônica e autoimune com
manifestações articulares e sistêmicas, e atinge cerca de 1% da população mundial …

W ostatnich latach znaczące postępy w medycynie przyczyniły się do wydłużenia długości
życia człowieka. Coraz większa skuteczność działania leków przeciwbakteryjnych i …

Objective Enthesitis-related arthritis (ERA) is associated with the increase in frequency of
Th17 cells and synovial fluid IL-17 levels. Recently, IL-15 and IL-18 has been shown to …

Rheumatoid Arthritis (RA) is a chronic systemic inflammatory disease, which targets the
synovial membrane and joints of patients, resulting in irreversible bone damage, and …

Mil veces he imaginado las primeras líneas de este este texto. Las mismas veces que he
ampliado la lista de nombres que debían aparecer, y ahora, llegado el momento, no sé …

Abstract IL-12 family members IL-12, IL-23, IL-27 and IL-35 are heterodimeric cytokines that
are important players in autoimmunity. Subunits are shared among the IL-12 family and …

Nerovnováha mezi aktivitou pro-a protizánětlivých cytokinů u revmatoidní artritidy (RA)
přispívá ke vzniku imunitní dysregulace, chronického zánětu a následné kloubní destrukce …