Laboratory assays for Epstein-Barr virus-related disease

ML Gulley, W Tang - The Journal of molecular diagnostics, 2008 - Elsevier
Epstein-Barr virus (EBV) infects various cell types in a wide spectrum of benign and
malignant diseases. Laboratory tests for EBV have improved and are increasingly used in …

Hemophagocytic lymphohistiocytosis (HLH): a heterogeneous spectrum of cytokine-driven immune disorders

E Brisse, CH Wouters, P Matthys - Cytokine & growth factor reviews, 2015 - Elsevier
Hemophagocytic lymphohistiocytosis (HLH) comprises a group of life-threatening immune
disorders classified into primary or secondary HLH. The former is caused by mutations in …

XIAP restricts TNF-and RIP3-dependent cell death and inflammasome activation

M Yabal, N Müller, H Adler, N Knies, CJ Groß… - Cell reports, 2014 - cell.com
X-linked inhibitor of apoptosis protein (XIAP) has been identified as a potent regulator of
innate immune responses, and loss-of-function mutations in XIAP cause the development of …

Treatment of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis (EBV-HLH); update 2010

S Imashuku - Journal of pediatric hematology/oncology, 2011 - journals.lww.com
The clinical features of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis (EBV-
HLH) vary significantly, from mild to severe, at the time of the treatment decision. There are …

X‐linked lymphoproliferative syndrome: a genetic condition typified by the triad of infection, immunodeficiency and lymphoma

N Rezaei, E Mahmoudi… - British journal of …, 2011 - Wiley Online Library
X‐linked lymphoproliferative disease (XLP) is an inherited immunodeficiency characterized
by the clinical triad of increased susceptibility to primary Epstein–Barr virus (EBV) infection …

An unusual cause of multiple organ dysfunction syndrome in the pediatric intensive care unit: hemophagocytic lymphohistiocytosis

B Karapinar, D Yilmaz, C Balkan, M Akin… - Pediatric Critical Care …, 2009 - journals.lww.com
Objective: To report our experience in children with primary or secondary hemophagocytic
lymphohistiocytosis (HLH) presented with multiple organ dysfunction syndrome (MODS) in …

HLH as an additional warning sign of inborn errors of immunity beyond familial-HLH in children: a systematic review

S Ricci, WM Sarli, L Lodi, C Canessa, F Lippi… - Frontiers in …, 2024 - frontiersin.org
Background Hemophagocytic Lymphohistiocytosis (HLH) is a rare and life-threatening
condition characterized by a severe impairment of the immune homeostasis. While Familial …

Comprehensive analyses and characterization of haemophagocytic lymphohistiocytosis in Vietnamese children

LT My, LB Lien, WC Hsieh, T Imamura… - British journal of …, 2010 - Wiley Online Library
Haemophagocytic lymphohistiocytosis (HLH) is a fatal haematological disorder with diverse
aetiology. This prospective study was undertaken to characterize HLH cases in Vietnamese …

Advanced therapeutic and prophylactic strategies for Epstein–Barr virus infection in immunocompromised patients

M Okano, TG Gross - Expert Review of Anti-Infective Therapy, 2007 - Taylor & Francis
Epstein–Barr virus (EBV) is an ubiquitous human herpesvirus. Primary infection is generally
subclinical but in certain circumstances, such as in patients with either hereditary or …

Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis in Los Angeles County

T Kelesidis, R Humphries, D Terashita… - Journal of medical …, 2012 - Wiley Online Library
Abstract Data on Epstein–Barr virus‐related hemophagocytic lymphohistiocytosis (EBV‐
HLH) in adults in the United States remain very limited. A cluster of four cases of EBV‐HLH …