Alcohol use disorders (AUDs) are complex traits, meaning that variations in many genes
contribute to the risk, as does the environment. Although the total genetic contribution to risk …

The liver metabolizes ethanol through three enzymatic pathways: alcohol dehydrogenase
(ADH), cytochrome p450 (also called MEOS), and catalase. Alcohol dehydrogenase class I …

Liability to alcohol dependence (AD) is heritable, but little is known about its complex
polygenic architecture or its genetic relationship with other disorders. To discover loci …

Objective: Alcohol use disorders are common conditions that have enormous social and
economic consequences. Genome-wide association analyses were performed to identify …

Alcohol use disorder (AUD) is a highly prevalent, comorbid, and disabling disorder. The
underlying mechanism of ethanol neurotoxicity and the involvement of oxidative stress is still …

Importance National epidemiologic information from recently collected data on the newDSM-
5classification of alcohol use disorder (AUD) using a reliable, valid, and uniform data source …

Genome-wide single nucleotide polymorphism (SNP) data are now quickly and
inexpensively acquired, raising the prospect of creating personalized dietary …

Alcoholism is a widespread and damaging behaviour of people throughout the world. Long-
term alcohol consumption has resulted in alcoholic liver disease (ALD) being the leading …

Methanol has been historically considered an exogenous product that leads only to
pathological changes in the human body when consumed. However, in normal, healthy …

Abstract Aims Alcohol Use Disorder (AUD) is a chronic psychiatric illness characterized by
harmful drinking patterns leading to negative emotional, physical, and social ramifications …