Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …

Cells have traditionally been viewed either as independently moving entities or as
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …

In this article, we review physics-based models of collective cell motility. We discuss a range
of techniques at different scales, ranging from models that represent cells as simple self …

In situ hybridization methods are used across the biological sciences to map mRNA
expression within intact specimens. Multiplexed experiments, in which multiple target …

Biologically-informed neural networks (BINNs), an extension of physics-informed neural
networks, are introduced and used to discover the underlying dynamics of biological …

Our understanding of the neural crest, a key vertebrate innovation, is built upon studies of
multiple model organisms. Early research on neural crest cells (NCCs) was dominated by …

From the initial discovery of the neural crest over 150 years ago to the seminal studies of Le
Douarin and colleagues in the latter part of the twentieth century, understanding of the …

Mathematical and computational models can assist in gaining an understanding of cell
behavior at many levels of organization. Here, we review models in the literature that focus …

Epithelial-to-mesenchymal transition (EMT) is a dynamic process that produces migratory
cells from epithelial precursors. However, EMT is not binary; rather it results in migratory …

Collective behaviors require coordination among a group of individuals. As a result,
individuals that are too phenotypically different from the rest of the group can be left out …