Epigenetic regulation of mitochondrial DNA (mtDNA) is an emerging and fast-developing
field of research. Compared to regulation of nucler DNA, mechanisms of mtDNA epigenetic …

Apoptosis is an evolutionarily conserved and tightly regulated cell death pathway.
Physiological cell death is important for maintaining homeostasis and optimal biological …

According to the World Health Organization (WHO), cancer is a leading cause of death
worldwide. The identification of novel targets for cancer treatment is an area of intense work …

Prostate cancer is one of the most common cancers among men. Currently available
therapies improve patient survival against local prostate cancer but have shown severe side …

The family of hexokinases (HKs) catalyzes the first step of glycolysis, the ATP-dependent
phosphorylation of glucose to glucose-6-phosphate. While HK1 and HK2 are ubiquitously …

Extracellular vesicles (EVs) have emerged as key mediators of intercellular communication
that have the potential to improve cardiac function when used in cell-based therapy …

Pyruvate kinase is a key regulator in glycolysis through the conversion of
phosphoenolpyruvate (PEP) into pyruvate. Pyruvate kinase exists in various isoforms that …

Cardiovascular disease (CVD) is the leading cause of death in the global population,
accounting for about one-third of all deaths each year. Notably, with CVDs, myocardial …

Cancer is a multifactorial disease that affects millions of people every year and is one of the
most common causes of death in the world. The high mortality rate is very often linked to late …

The sensitivity of cells to chemotherapeutic agents has a major effect on disease outcome in
breast cancer patients. Unfortunately, there are numerous factors involved in the regulation …