Ovarian cancer is the most lethal of all of the gynecological cancers and can arise from any
cell type of the ovary, including germ cells, granulosa or stromal cells. However, the majority …

The Atlas of Tumor Pathology has a long and distinguished history. It was first conceived at a
Cancer Research Meeting held in St. Louis in September 1947 as an attempt to standardize …

Comparative hybridization of cDNA arrays is a powerful tool for the measurement of
differences in gene expression between two or more tissues. We optimized this technique …

DNA amplification at chromosomal region 20q12-q13, which is common in breast cancer,
has recently been described also in ovarian tumors. We studied the amplification of the …

An intraovarian role for steroids in periovulatory events was postulated as far back as the
early 1970s, when Rondell hypothesized that steroids facilitate the actions of gonadotropins …

The identification of new proliferation markers could have clinical implications in ovarian
carcinoma by stratifying patients for treatment and follow-up. The aim of this study was to …

Ovarian cancer is the leading cause of gynecological cancer mortality, and 85–90% of this
malignancy originates from the ovarian surface epithelium (OSE). The etiology of ovarian …

Targeting molecular markers and pathways implicated in cancer cell growth is a promising
avenue for developing effective therapies. Although the Ki-67 protein (pKi-67) is a key …

Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer
commonly resistant to therapeutics that have been successful in increasing survival in …

The purpose of this study was to evaluate the biological significance of Ki67 antigen
expression in serous ovarian tumors, through the analysis of MIB 1 monoclonal antibody …