Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Background Diagnosing invasive or chronic fungal infections is a challenge, particularly in
the immunocompromised host. Microscopy and culture remain the reference standard, but …

The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

Invasive pulmonary aspergillosis (IPA) remains difficult to diagnose and to treat. Most
common risk factors are prolonged neutropenia, hematopoietic stem cell or solid organ …

Background The International Society for Human and Animal Mycology (ISHAM) working
group proposed recommendations for managing allergic bronchopulmonary aspergillosis …

Abstract Purpose of Review To understand the role of antibody detection in the diagnosis of
infections caused by filamentous fungi (molds). Rapid and accurate profiling of infection …

Early detection is critical to the successful treatment of life-threatening infections caused by
fungal pathogens, as late diagnosis of systemic infection almost always equates with a poor …

BACKGROUND The fungus Aspergillus fumigatus causes a variety of clinical phenotypes in
patients with cystic fibrosis (pwCF). Th cells orchestrate immune responses against fungi …

ABSTRACT Detecting Aspergillus-specific IgG is critical to diagnosing chronic pulmonary
aspergillosis (CPA). Existing assays are often cost-and resource-intensive and not …

Introduction Fungal disease has historically presented a diagnostic challenge due to its
often non-specific clinical presentations, relative infrequency and reliance on insensitive and …