Coffee is one of the most widely consumed beverages worldwide. It is usually identified as a
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …

Neurodegenerative diseases (NDDs) are characterized by selective dysfunction and loss of
neurons associated with pathologically altered proteins that deposit in the human brain but …

Frontotemporal lobar degeneration (FTLD) is the third most common neurodegenerative
condition after Alzheimer's and Parkinson's diseases. FTLD typically presents in 45 to 64 …

Objectives: To estimate the lifetime risk, prevalence, incidence, and mortality of the principal
clinical syndromes associated with frontotemporal lobar degeneration (FTLD) using revised …

To define how the C9orf72 GGGGCC expansion mutation causes ALS/FTD and to facilitate
therapy development, a mouse model that recapitulates the molecular and phenotypic …

Neurodegenerative diseases are characterised by selective dysfunction and progressive
loss of synapses and neurons associated with pathologically altered proteins that deposit …

Alzheimer's disease, the commonest cause of dementia, is a growing global health concern
with huge implications for individuals and society. In this review, current understanding of …

Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a
heterogeneous neurodegenerative disease characterized by progressive behavioural …

Background: Frontotemporal dementia (FTD) describes a cluster of neurocognitive
syndromes that present with impairment of executive functioning, changes in behavior, and …

Accumulation of abnormally phosphorylated TDP-43 (pTDP-43) is the main pathology in
affected neurons of people with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar …