Lipid phosphoinositides are master regulators of almost all aspects of a cell's life and death
and are generated by the tightly regulated activity of phosphoinositide kinases. Although …

Inositols are sugar-like compounds that are widely distributed in nature and are a part of
membrane molecules, participating as second messengers in several cell-signaling …

Metastatic urothelial carcinoma is generally incurable with current systemic therapies.
Chromatin modifiers are frequently mutated in bladder cancer, with ARID1A-inactivating …

Lipid phosphoinositides are master signaling molecules in eukaryotic cells and key markers
of organelle identity. Because of these important roles, the kinases and phosphatases that …

Cytidine diphosphate diacylglycerol (CDP-DAG) is a key intermediate in the synthesis of
phosphatidylinositol (PI) and cardiolipin (CL). Both PI and CL have highly specialized roles …

Abnormalities in the endosomal-autophagic-lysosomal (EAL) system are an early event in
Alzheimer's disease (AD) pathogenesis. However, the mechanisms underlying these …

Alzheimer's disease is one of the neurodegenerative diseases, characterized by the
accumulation of abnormal protein deposits, which disrupts signal transduction in neurons …

Phosphoinositides are a family of membrane phospholipids that play crucial roles in
membrane regulatory events. As such, these lipids are often a key part of molecular …

Egg yolk contains very high levels of lipids, which comprise 33% of whole egg yolk.
Although triglyceride is the main lipid, egg yolk is the richest source of phospholipids and …

The mechanisms underlying Parkinson's disease (PD) etiology are only partially understood
despite intensive research conducted in the field. Recent evidence suggests that early …