Chronic pain is one of the most prevalent health problems in our modern world, with millions
of people debilitated by conditions such as back pain, headache and arthritis. To address …

Our understanding of the mechanisms mediating or moderating the placebo response to
medicines has grown substantially over the past decade and offers the opportunity to …

Modern medicine has progressed in parallel with the advancement of biochemistry,
anatomy, and physiology. By using the tools of modern medicine, the physician today can …

Pharmacological strategies for pain management have primarily focused on dampening
ascending neurotransmission and on opioid receptor–mediated therapies. Little is known …

Today we are witnessing a new science of placebo, a complex discipline that encompasses
several experimental approaches and translational implications. Modern neurobiological …

Despite growing scientific interest in the placebo effect and increasing understanding of
neurobiological mechanisms, theoretical conceptualization of the placebo effect remains …

Stay current in the ever-changing discipline of rheumatology with clear, reliable guidance
from Hochberg's Rheumatology, one of the most respected and trusted sources in the field …

Placebos have been used ubiquitously throughout the history of medicine. Expectations and
associative learning processes are important psychological determinants of placebo effects …

Placebo analgesia is mediated by both opioid and nonopioid mechanisms, but so far
nothing is known about the nonopioid component. Here we show that the specific CB1 …

Scientific research indicates that open-label and dose-extending placebos (that patients
know are placebos) can elicit behavioral, biological, and clinical outcome changes. In this …