Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

Pancreatic cancer is a highly malignant and incurable disease, characterized by its
aggressive nature and high fatality rate. The most common type is pancreatic ductal …

Pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, is
characterized by poor treatment response and low survival time. The current clinical …

Pancreatic cancer is an aggressive malignancy with increasing incidence and poor
prognosis due to its late diagnosis and intrinsic chemoresistance. Most pancreatic cancer …

Background Immunotherapy of gastrointestinal cancers is challenging; however, several
lines of evidence suggest that adoptive transfer of stimulated or modified immune cells …

The intrinsic features and functions of platelets and mesenchymal stem cells (MSCs)
indicate their great potential in the treatment of intracerebral hemorrhage (ICH). However …

Pancreatic cancer is a highly aggressive malignancy that features high recurrence rates and
the poorest prognosis of all solid cancers. The urokinase plasminogen activation system …

Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive
tumors with an extremely low 5-year survival rate. Accumulating evidence has unveiled that …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC), the most common form of
pancreatic cancer, remains one of the most lethal diseases. Current evidence, discussed in …

Simple Summary Pancreatic cancer is one of the most lethal cancers. Although complete
surgical resection is the only curative treatment for pancreatic cancer, a late diagnosis is …