[HTML][HTML] Bioavailability, efficacy, safety, and regulatory status of creatine and related compounds: A critical review

RB Kreider, R Jäger, M Purpura - Nutrients, 2022 - mdpi.com
In 2011, we published a paper providing an overview about the bioavailability, efficacy, and
regulatory status of creatine monohydrate (CrM), as well as other “novel forms” of creatine …

[HTML][HTML] Oxidative stress gene expression, DNA methylation, and gut microbiota interaction trigger Crohn's disease: a multi-omics Mendelian randomization study

S Xu, X Li, S Zhang, C Qi, Z Zhang, R Ma, L Xiang… - BMC medicine, 2023 - Springer
Background Oxidative stress (OS) is a key pathophysiological mechanism in Crohn's
disease (CD). OS-related genes can be affected by environmental factors, intestinal …

Arginine metabolism regulates the pathogenesis of inflammatory bowel disease

JY Li, YC Guo, HF Zhou, TT Yue, FX Wang… - Nutrition …, 2023 - academic.oup.com
The pathogenesis of inflammatory bowel disease (IBD) is related to genetic susceptibility,
enteric dysbiosis, and uncontrolled, chronic inflammatory responses that lead to colonic …

[HTML][HTML] Metabolic landscape of the male mouse gut identifies different niches determined by microbial activities

KHU Meier, J Trouillon, H Li, M Lang, T Fuhrer… - Nature …, 2023 - nature.com
Distinct niches of the mammalian gut are populated by diverse microbiota, but the
contribution of spatial variation to intestinal metabolism remains unclear. Here we present a …

[HTML][HTML] Revisiting the “starved gut” hypothesis in inflammatory bowel disease

SP Colgan, RX Wang, CHT Hall… - …, 2023 - journals.lww.com
Active episodes of inflammatory bowel disease (IBD), which include ulcerative colitis and
Crohn's disease, coincide with profound shifts in the composition of the microbiota and host …

[HTML][HTML] Creatine enhances the effects of cluster-set resistance training on lower-limb body composition and strength in resistance-trained men: a pilot study

DA Bonilla, RB Kreider, JL Petro, R Romance… - Nutrients, 2021 - mdpi.com
Creatine monohydrate (CrM) supplementation has been shown to improve body
composition and muscle strength when combined with resistance training (RT); however, no …

[HTML][HTML] Mitochondria of intestinal epithelial cells in depression: Are they at a crossroads of gut-brain communication?

Y Wang, H Lai, T Zhang, J Wu, H Tang, X Liang… - Neuroscience & …, 2023 - Elsevier
The role of gut dysbiosis in depression is well established. However, recent studies have
shown that gut microbiota is regulated by intestinal epithelial cell (IEC) mitochondria, which …

[HTML][HTML] Anti-inflammatory and anti-catabolic effects of creatine supplementation: A brief review

DM Cordingley, SM Cornish, DG Candow - Nutrients, 2022 - mdpi.com
It is well established that creatine supplementation, primarily when combined with resistance
training, significantly increases measures of muscle mass and performance (primarily …

[HTML][HTML] Multiomics Strategy Reveals the Mechanism of Action and Ameliorating Effect of Deer Velvet Antler Water Extracts on DSS-Induced Colitis

YK Hung, ST Ho, CY Kuo, MJ Chen - Biomedicines, 2023 - mdpi.com
Velvet antler is a precious traditional Chinese medicine used for thousands of years. This
study investigated the anti-colitis effects of water extracts of Formosan sambar deer (SVAE) …

[HTML][HTML] A convergent functional genomics analysis to identify biological regulators mediating effects of creatine supplementation

DA Bonilla, Y Moreno, ES Rawson, DA Forero… - Nutrients, 2021 - mdpi.com
Creatine (Cr) and phosphocreatine (PCr) are physiologically essential molecules for life,
given they serve as rapid and localized support of energy-and mechanical-dependent …