Introduction Antimicrobial resistance (AMR) is responsible for the death of millions
worldwide and stands as a major threat to our healthcare systems, which are heavily reliant …

HMOs (human milk oligosaccharides) are the third most important nutrient in breast milk. As
complex glycans, HMOs play an important role in regulating neonatal intestinal immunity …

Vaccines remain one of the most important pillars in preventative medicine, providing
protection against a wide array of diseases by inducing humoral and/or cellular immunity. Of …

Many glycosylated small molecule natural products and glycoprotein biologics are important
in a broad range of therapeutic and industrial applications. The sugar moieties that decorate …

Cancer cells need as much as 40-times more sugar than their normal cell counterparts. This
sugar demand is attained by the excessive expression of inimitable transporters on the …

Glycosylation is the most prominent modification important for vaccines and its specific
pattern depends on several factors that need to be considered when developing a new …

Protonated ions of fucose-containing oligosaccharides are prone to undergo internal glycan
rearrangement which results in chimeric fragments that obfuscate mass-spectrometric …

Glycoconjugate vaccines have contributed enormously to reducing and controlling
encapsulated bacterial infections for over thirty years. Glycoconjugate vaccines are based …

Lectins, carbohydrate-binding proteins, play important functions in all forms of life from
bacteria and viruses to plants, animals, and humans, participating in cell–cell …

The non-covalent associations of complex carbohydrates (glycans) with glycan-binding
proteins mediate many important physiological and pathophysiological processes …