How to master the host immune system? Leishmania parasites have the solutions!

M Rossi, N Fasel - International immunology, 2018 - academic.oup.com
Infection by protozoan parasites of the genus Leishmania results in the development of
leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people …

[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

EK Elmahallawy, AAM Alkhaldi, AA Saleh - Biomedicine & …, 2021 - Elsevier
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

Cell type-specific regulation of IL-10 expression in inflammation and disease

CM Hedrich, JH Bream - Immunologic research, 2010 - Springer
IL-10 plays an essential part in controlling inflammation and instructing adaptive immune
responses. Consequently, dysregulation of IL-10 is linked with susceptibility to numerous …

Mechanisms of immune evasion induced by a complex of dengue virus and preexisting enhancing antibodies

S Ubol, W Phuklia, S Kalayanarooj… - The Journal of …, 2010 - academic.oup.com
We have found that dengue virus (DENV) not only uses preexisting enhancing antibodies to
promote its entry into Fc receptor-bearing cells but also exploits enhancing antibodies for …

The immunology of post-kala-azar dermal leishmaniasis (PKDL)

EE Zijlstra - Parasites & vectors, 2016 - Springer
Post-kala-azar dermal leishmaniasis (PKDL) is a common complication of visceral
leishmaniasis (VL) caused by Leishmania donovani. Because of its possible role in …

Immune regulation during chronic visceral leishmaniasis

RJ Faleiro, R Kumar, LM Hafner… - PLoS neglected tropical …, 2014 - journals.plos.org
Visceral leishmaniasis is a chronic parasitic disease associated with severe immune
dysfunction. Treatment options are limited to relatively toxic drugs, and there is no vaccine …

[HTML][HTML] Post kala-azar dermal leishmaniasis: an unresolved mystery

D Mukhopadhyay, JE Dalton, PM Kaye… - Trends in …, 2014 - cell.com
Post kala-azar dermal leishmaniasis (PKDL), a cutaneous sequela of visceral leishmaniasis
(VL), develops in some patients alongside but more commonly after apparent cure from VL …

Post kala-azar dermal leishmaniasis: A threat to elimination program

MR Gedda, B Singh, D Kumar, AK Singh… - PLoS Neglected …, 2020 - journals.plos.org
Leishmaniasis remains a public health concern around the world that primarily affects poor
folks of the developing world spanning across 98 countries with mortality of 0.2 million to 0.4 …

Targeted killing of Leishmania donovani in vivo and in vitro with amphotericin B attached to functionalized carbon nanotubes

VK Prajapati, K Awasthi, S Gautam… - Journal of …, 2011 - academic.oup.com
Objectives This study describes the antileishmanial efficacy of the novel drug formulation of
amphotericin B (AmB) attached to functionalized carbon nanotubes (f-CNTs) and compares …

Efficacy of artemisinin in experimental visceral leishmaniasis

R Sen, S Ganguly, P Saha, M Chatterjee - International Journal of …, 2010 - Elsevier
Visceral leishmaniasis (VL), caused by the protozoan Leishmania sp., affects 500000
people annually, with the Indian subcontinent contributing a significant proportion of these …