This systematic review has examined more than 300 original papers dealing with the
biology of overfeeding. Studies have varied from 1 day to 6 months. Overfeeding produced …

Fructose is a physiological nutrient which, when consumed in excess, may have adverse
metabolic effects, mainly in the liver (hepatic insulin resistance and fat storage). There is …

In the context of high human consumption of fructose diets, there is an imperative need to
understand how dietary fructose intake influence cellular and molecular mechanisms and …

Increased hepatic lipid content and decreased insulin sensitivity have critical roles in the
development of cardiometabolic diseases. Therefore, our objective was to investigate the …

Understanding how individuals react differently to the same treatment is a major concern in
precision medicine. Metabolic challenges such as the one posed by high fructose intake are …

Background and aim Type 2 diabetes is one of the global epidemic disorders, which causes
many side effects on the body. Fructose is a lipogenic monosaccharide. Recent studies have …

Consumption of fructose has dramatically increased in past few decades in children and
adults. Increasing evidence indicates that added sugars (particularly fructose) have adverse …

Two randomized placebo-controlled double-blind paralleled trials (42 men in Lyon, 19
women in Lausanne) were designed to test 2 g/day of a grape polyphenol extract during 31 …

Background and aims Excessive intake of fructose is a significant contributor in the
development of hypertension and pathogenesis of cardiometabolic diseases. We previously …

Increased hepatic lipid content and decreased insulin sensitivity have critical roles in the
development of cardiometabolic diseases. Therefore, our objective was to investigate the …