Moyamoya disease (MMD) is a rare cerebrovascular disease characterized by progressive
spontaneous bilateral occlusion of the intracranial internal cerebral arteries (ICA) and their …

Moyamoya disease (MMD) is a rare cerebrovascular disorder with unknown etiology. MMD
is characterized by progressive narrowing of arteries of the brain and the formation of a …

Objective To test the hypothesis that de novo genetic variants are responsible for moyamoya
disease (MMD) in children with unaffected relatives, we performed exome sequencing of 28 …

Background and Purpose—A growing body of evidence indicates genetic components play
critical roles in moyamoya disease (MMD). Firm conclusions from studies of this disease …

The ring finger protein 213 gene (RNF213) encodes a 590 kDa protein that is thought to be
involved in angiogenesis. This gene was first recognized as a vasculopathy-susceptibility …

The genetic background of intracranial artery stenosis (ICAS), a major cause of ischemic
stroke, remains elusive. We performed the world's first genome-wide association study …

Pulmonary arterial hypertension (PAH) mainly occurs as a result of abnormal proliferation
and apoptosis resistance of pulmonary artery smooth muscle cells (PASMCs). Endothelial …

Background: The evidence regarding triple oral combination therapy for patients with
pulmonary arterial hypertension (PAH) is scarce. This study was performed to investigate the …

Moyamoya disease (MMD) is a cerebrovascular disorder characterized by a steno-occlusive
internal carotid artery and compensatory vascular network formation. Although the precise …

Systemic vasculopathy has occasionally been reported in cases of moyamoya disease
(MMD). Since the pathological relationship between moyamoya vasculopathy (MMV) and …