A pharmacological update of ellagic acid

JL Ríos, RM Giner, M Marín, MC Recio - Planta medica, 2018 - thieme-connect.com
Ellagic acid is a common metabolite present in many medicinal plants and vegetables. It is
present either in free form or as part of more complex molecules (ellagitannins), which can …

Dietary phytochemicals in colorectal cancer prevention and treatment: A focus on the molecular mechanisms involved

S Afrin, F Giampieri, M Gasparrini… - Biotechnology …, 2020 - Elsevier
Worldwide, colorectal cancer (CRC) remains a major cancer type and leading cause of
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …

An integrated approach for the valorization of mango seed kernel: Efficient extraction solvent selection, phytochemical profiling and antiproliferative activity …

D Ballesteros-Vivas, G Álvarez-Rivera… - Food Research …, 2019 - Elsevier
A novel valorization strategy is proposed in this work for the sustainable utilization of a major
mango processing waste (ie mango seed kernel, MSK), integrating green pressurized-liquid …

Synergism of ellagic acid in combination with radiotherapy and chemotherapy for cancer treatment

P Xue, G Zhang, J Zhang, L Ren - Phytomedicine, 2022 - Elsevier
Background Ellagic acid (EA) is a polyphenol compound abundant in berries, walnuts,
pecans, pomegranate, cranberries, and other plant foods and exerts a wide array of …

The effects of ellagic acid and other pomegranate (Punica granatum L.) derivatives on human gastric cancer AGS cells

H Cheshomi, AR Bahrami… - Human & …, 2022 - journals.sagepub.com
Although surgery with or without (neo) adjuvant chemo/radiotherapy, as the standard
treatments, can be suitable therapeutic strategies for gastric cancer, side effects and drug …

Simultaneous hydrolysis of ellagitannins and extraction of ellagic acid from defatted raspberry seeds using natural deep eutectic solvents (NADES)

N Teslić, F Santos, F Oliveira, A Stupar, M Pojić… - Antioxidants, 2022 - mdpi.com
Defatted raspberry seeds were used as an alternative source of antioxidants and ellagic
acid (EA) extracted using Natural deep eutectic solvents (NADES). In the preliminary study …

Phytochemical Profiling of Extracts from Rare Potentilla Species and Evaluation of Their Anticancer Potential

D Augustynowicz, MK Lemieszek, JW Strawa… - International Journal of …, 2023 - mdpi.com
Despite the common use of Potentilla L. species (Rosaceae) as herbal medicines, a number
of species still remain unexplored. Thus, the present study is a continuation of a study …

RETRACTED: Chitosan-Based Microparticles Enhance Ellagic Acid's Colon Targeting and Proapoptotic Activity

NA Alhakamy, OAA Ahmed, M Kurakula, G Caruso… - Pharmaceutics, 2020 - mdpi.com
This study aimed at improving the targeting and cytotoxic effect of ellagic acid (EA) on colon
cancer cells. EA was encapsulated in chitosan (CHIT) polymers then coated by eudragit …

In vitro combination of ascorbic and ellagic acids in sperm oxidative damage inhibition

F Mottola, C Iovine, M Carannante… - International Journal of …, 2022 - mdpi.com
It is known that an altered redox balance interferes with normal spermatic functions.
Exposure to genotoxic substances capable of producing oxidative stress (OS) can cause …

Protective activity of ellagic acid in counteract oxidative stress damage in zebrafish embryonic development

F Mottola, N Scudiero, C Iovine, M Santonastaso… - Ecotoxicology and …, 2020 - Elsevier
During its development, embryo is easily susceptible to reactive oxygen species (ROS).
Evidence demonstrate protective role of the antioxidants, improving both cellular growth and …