Glycosylation is the most abundant and diverse form of post-translational modification of
proteins that is common to all eukaryotic cells. Enzymatic glycosylation of proteins involves a …

Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …

Tumour growth is accompanied by tumour evasion of the immune system, a process that is
facilitated by immune checkpoint molecules such as programmed cell death protein 1 (PD1) …

N-linked glycosylation is a post-translational modification crucial for membrane protein
folding, stability and other cellular functions. Alteration of membrane protein N-glycans is …

Researches on the microbiome have been actively conducted worldwide and the results
have shown human gut bacterial environment significantly impacts on immune system …

Protein glycosylation represents a nearly ubiquitous post-translational modification, and
altered glycosylation can result in clinically significant pathological consequences. Here we …

Changes in mucin-type O-linked glycosylation are seen in over 90% of breast cancers
where increased sialylation is often observed and a change from branched glycans to linear …

The tumour microenvironment plays a crucial role in the growth and progression of cancer,
and the presence of tumour-associated macrophages (TAMs) is associated with poor …

Glioblastoma is the most aggressive brain malignancy, for which immunotherapy has failed
to prolong survival. Glioblastoma-associated immune infiltrates are dominated by tumor …

Simple Summary Cancer-associated glycosylation changes are widely used as biomarkers
and strongly impact malignancy. However, the clinical significance of the deranged …