Vitamin d metabolic pathway genes polymorphisms and their methylation levels in association with rheumatoid arthritis

TP Zhang, HM Li, Q Huang, L Wang, XM Li - Frontiers in immunology, 2021 - frontiersin.org
Abnormal vitamin D metabolism is involved in the pathogenesis of rheumatoid arthritis (RA).
In this study, we evaluated the association of single nucleotide polymorphisms (SNPs) and …

Contribution of CYP24A1 variants in coronary heart disease among the Chinese population

P Qian, X Cao, X Xu, M Duan, Q Zhang… - Lipids in health and …, 2020 - Springer
Abstract Background Cytochrome P450 (CYPs) participate in the mechanisms of
cardiovascular disease. The purpose of this research was to evaluate the contributions of …

CYP11B1 gene polymorphisms and susceptibility to ischemic stroke in a Chinese Han population

G Liu, Y Duan - Frontiers in Neuroscience, 2022 - frontiersin.org
Objectives Ischemic stroke (IS) is the major cause of death and disability. While previous
studies confirmed that CYP11B1 is closely associated with IS, the present study aimed to …

Genetic loci, rs17817449 and rs6567160, known for obesity and the risk of stroke events among middle-aged and older Chinese people

QQ Zhong, F Zhu - Frontiers in Neurology, 2022 - frontiersin.org
Background Fat Mass and Obesity-Associated (FTO) and the Melanocortin-4 Receptor
(MC4R) genes are strongly associated with obesity, an established risk factor for stroke. We …

The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility

Y Zhao, Q Zhang, X Zhang, Y Zhang, Y Lu… - Brain and …, 2022 - Wiley Online Library
Background Ischemic stroke (IS), a multifactorial and polygenic disease, is the most common
cause of death. This study aimed to determine the roles of MMP8/MMP10 polymorphisms in …

Genetic variants associated with mineral metabolism traits in chronic kidney disease

ML Laster, B Rowan, HC Chen… - The Journal of …, 2022 - academic.oup.com
Context Chronic kidney disease (CKD) causes multiple interrelated disturbances in mineral
metabolism. Genetic studies in the general population have identified common genetic …

SNPs in cytochrome P450 genes decide on the fate of individuals with genetic predisposition to Parkinson's disease

P Petkova-Kirova, S Baas, G Wagenpfeil… - Frontiers in …, 2023 - frontiersin.org
Parkinson's disease (PD) is one of the most frequent neurological diseases affecting millions
of people worldwide. While the majority of PD cases are of unknown origin (idiopathic) …

Genetic polymorphisms in pri-let-7a-2 are associated with ischemic stroke risk in a Chinese Han population from Liaoning, China: a case-control study

YY Wang, HY Zhang, WJ Jiang, F Liu, L Li… - Neural Regeneration …, 2021 - journals.lww.com
Ischemic stroke is a complicated disease, and its pathogenesis has been attributed to the
occurrence of genetic polymorphisms. Evidence has suggested that the microRNA let-7a is …

Associations of vitamin D-related single nucleotide polymorphisms with post-stroke depression among ischemic stroke population

D Sun, M Song, C Zeng, H Chen, J Zhang, F Liu… - Frontiers in …, 2023 - frontiersin.org
Objective To investigate the relationship between single nucleotide polymorphisms (SNPs)
related to vitamin D (VitD) metabolism and post-stroke depression (PSD) in patients with …

Association of CYP4A22 gene polymorphisms with cerebral stroke risk in the Chinese Han population

Q Zhuo, X Zhong, J Wen, Y Ding - The Journal of Gene …, 2023 - Wiley Online Library
Background Cerebral stroke (stroke) is an acute cerebrovascular disease with high
incidence and mortality. This study aimed to explore the association between single …