Vitamin d metabolic pathway genes polymorphisms and their methylation levels in association with rheumatoid arthritis
TP Zhang, HM Li, Q Huang, L Wang, XM Li - Frontiers in immunology, 2021 - frontiersin.org
Abnormal vitamin D metabolism is involved in the pathogenesis of rheumatoid arthritis (RA).
In this study, we evaluated the association of single nucleotide polymorphisms (SNPs) and …
In this study, we evaluated the association of single nucleotide polymorphisms (SNPs) and …
Contribution of CYP24A1 variants in coronary heart disease among the Chinese population
P Qian, X Cao, X Xu, M Duan, Q Zhang… - Lipids in health and …, 2020 - Springer
Abstract Background Cytochrome P450 (CYPs) participate in the mechanisms of
cardiovascular disease. The purpose of this research was to evaluate the contributions of …
cardiovascular disease. The purpose of this research was to evaluate the contributions of …
CYP11B1 gene polymorphisms and susceptibility to ischemic stroke in a Chinese Han population
G Liu, Y Duan - Frontiers in Neuroscience, 2022 - frontiersin.org
Objectives Ischemic stroke (IS) is the major cause of death and disability. While previous
studies confirmed that CYP11B1 is closely associated with IS, the present study aimed to …
studies confirmed that CYP11B1 is closely associated with IS, the present study aimed to …
Genetic loci, rs17817449 and rs6567160, known for obesity and the risk of stroke events among middle-aged and older Chinese people
QQ Zhong, F Zhu - Frontiers in Neurology, 2022 - frontiersin.org
Background Fat Mass and Obesity-Associated (FTO) and the Melanocortin-4 Receptor
(MC4R) genes are strongly associated with obesity, an established risk factor for stroke. We …
(MC4R) genes are strongly associated with obesity, an established risk factor for stroke. We …
The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility
Y Zhao, Q Zhang, X Zhang, Y Zhang, Y Lu… - Brain and …, 2022 - Wiley Online Library
Background Ischemic stroke (IS), a multifactorial and polygenic disease, is the most common
cause of death. This study aimed to determine the roles of MMP8/MMP10 polymorphisms in …
cause of death. This study aimed to determine the roles of MMP8/MMP10 polymorphisms in …
Genetic variants associated with mineral metabolism traits in chronic kidney disease
Context Chronic kidney disease (CKD) causes multiple interrelated disturbances in mineral
metabolism. Genetic studies in the general population have identified common genetic …
metabolism. Genetic studies in the general population have identified common genetic …
SNPs in cytochrome P450 genes decide on the fate of individuals with genetic predisposition to Parkinson's disease
P Petkova-Kirova, S Baas, G Wagenpfeil… - Frontiers in …, 2023 - frontiersin.org
Parkinson's disease (PD) is one of the most frequent neurological diseases affecting millions
of people worldwide. While the majority of PD cases are of unknown origin (idiopathic) …
of people worldwide. While the majority of PD cases are of unknown origin (idiopathic) …
Genetic polymorphisms in pri-let-7a-2 are associated with ischemic stroke risk in a Chinese Han population from Liaoning, China: a case-control study
YY Wang, HY Zhang, WJ Jiang, F Liu, L Li… - Neural Regeneration …, 2021 - journals.lww.com
Ischemic stroke is a complicated disease, and its pathogenesis has been attributed to the
occurrence of genetic polymorphisms. Evidence has suggested that the microRNA let-7a is …
occurrence of genetic polymorphisms. Evidence has suggested that the microRNA let-7a is …
Associations of vitamin D-related single nucleotide polymorphisms with post-stroke depression among ischemic stroke population
D Sun, M Song, C Zeng, H Chen, J Zhang, F Liu… - Frontiers in …, 2023 - frontiersin.org
Objective To investigate the relationship between single nucleotide polymorphisms (SNPs)
related to vitamin D (VitD) metabolism and post-stroke depression (PSD) in patients with …
related to vitamin D (VitD) metabolism and post-stroke depression (PSD) in patients with …
Association of CYP4A22 gene polymorphisms with cerebral stroke risk in the Chinese Han population
Q Zhuo, X Zhong, J Wen, Y Ding - The Journal of Gene …, 2023 - Wiley Online Library
Background Cerebral stroke (stroke) is an acute cerebrovascular disease with high
incidence and mortality. This study aimed to explore the association between single …
incidence and mortality. This study aimed to explore the association between single …