PERP-ing into diverse mechanisms of cancer pathogenesis: Regulation and role of the p53/p63 effector PERP

O Roberts, L Paraoan - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2020 - Elsevier
The tetraspan plasma membrane protein PERP (p53 apoptosis effector related to PMP22) is
a lesser-known transcriptional target of p53 and p63. A member of the PMP22/GAS3/EMP …

DCAF13 promotes breast cancer cell proliferation by ubiquitin inhibiting PERP expression

BQ Shan, XM Wang, L Zheng, Y Han, J Gao… - Cancer …, 2022 - Wiley Online Library
Evolutionarily conserved DDB1‐and CUL4‐associated factor 13 (DCAF13) is a recently
discovered substrate receptor for the cullin RING‐finger ubiquitin ligase 4 (CRL4) E3 …

[HTML][HTML] The NEAT1_2/miR-491 Axis Modulates Papillary Thyroid Cancer Invasion and Metastasis Through TGM2/NFκb/FN1 Signaling

W Sun, Y Qin, Z Wang, W Dong, L He, T Zhang… - Frontiers in …, 2021 - frontiersin.org
NEAT1 (nuclear paraspeckle assembly transcript 1) is an oncogenic long non-coding RNA
(lncRNA) that facilitates tumorigenesis in multiple cancers. In papillary thyroid cancer (PTC) …

[HTML][HTML] Multi-omics analysis reveals a molecular landscape of the early recurrence and early metastasis in pan-cancer

D He, N Wang, XL Wen, XH Li, Y Guo, S Fu… - Frontiers in …, 2023 - frontiersin.org
Cancer remains a formidable challenge in medicine due to its propensity for recurrence and
metastasis, which can result in unfavorable treatment outcomes. This challenge is …

[HTML][HTML] Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression

J Chu, L Tao, T Yao, Z Chen, X Lu, L Gao, L Fang… - Cell Death & …, 2021 - nature.com
Papillary thyroid cancer (PTC) has a continuously increasing incidence and imposes a
heavy medical burden to individuals and society due to its high proportion of lymph node …

[HTML][HTML] Intraoperative MET-receptor targeted fluorescent imaging and spectroscopy for lymph node detection in papillary thyroid cancer: novel diagnostic tools for …

PKC Jonker, MJH Metman, LHJ Sondorp… - European Journal of …, 2022 - Springer
Purpose Patients undergoing prophylactic central compartment dissection (PCLND) for
papillary thyroid cancer (PTC) are often overtreated. This study aimed to determine if …

[HTML][HTML] Identification of hub genes in papillary thyroid carcinoma: robust rank aggregation and weighted gene co-expression network analysis

Y Liu, TY Chen, ZY Yang, W Fang, Q Wu… - Journal of translational …, 2020 - Springer
Background Papillary thyroid carcinoma (PTC), which is the most common endocrine
malignancy, has been steadily increasing worldwide in incidence over the years, while …

[HTML][HTML] In silico analysis of ion channels and their correlation with epithelial to mesenchymal transition in breast cancer

KTS Parthasarathi, S Mandal, S Singh, S Gundimeda… - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer involves changes in the healthy cells of the breast resulting
in rapid and abnormal division of cells that later spread to other parts of the body through the …

[HTML][HTML] Radiogenomic analysis of papillary thyroid carcinoma for prediction of cervical lymph node metastasis: a preliminary study

Y Tong, P Sun, J Yong, H Zhang, Y Huang… - Frontiers in …, 2021 - frontiersin.org
Background Papillary thyroid carcinoma (PTC) is characterized by frequent metastases to
cervical lymph nodes (CLNs), and the presence of lymph node metastasis at diagnosis has …

[HTML][HTML] Risk score based on expression of five novel genes predicts survival in soft tissue sarcoma

HY Gu, C Zhang, J Guo, M Yang, HC Zhong… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Abstract In this study, The Cancer Genome Atlas and Genotype-Tissue Expression
databases were used to identify potential biomarkers of soft tissue sarcoma (STS) and …