[HTML][HTML] Inflammasome activation and regulation: toward a better understanding of complex mechanisms
Inflammasomes are cytoplasmic multiprotein complexes comprising a sensor protein,
inflammatory caspases, and in some but not all cases an adapter protein connecting the two …
inflammatory caspases, and in some but not all cases an adapter protein connecting the two …
[HTML][HTML] The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation
HA Saleh, MH Yousef, A Abdelnaser - Frontiers in immunology, 2021 - frontiersin.org
Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …
[HTML][HTML] Pre-and post-harvest factors affecting glucosinolate content in broccoli
Owing to several presumed health-promoting biological activities, increased attention is
being given to natural plant chemicals, especially those frequently entering the human diet …
being given to natural plant chemicals, especially those frequently entering the human diet …
Sulforaphane as a potential remedy against cancer: Comprehensive mechanistic review
Sulforaphane belongs to the active class of isothiocyanates capable of delivering various
biological benefits for health promotion and disease prevention. This compound is …
biological benefits for health promotion and disease prevention. This compound is …
Inhibitory effects of sulforaphane on NLRP3 inflammasome activation
SFN, a dietary phytochemical, is a significant member of isothiocyanates present in
cruciferous vegetables at high levels in broccoli. It is a well-known activator of the Nrf2/ARE …
cruciferous vegetables at high levels in broccoli. It is a well-known activator of the Nrf2/ARE …
Cruciferous vegetables: rationale for exploring potential salutary effects of sulforaphane-rich foods in patients with chronic kidney disease
LFMF Cardozo, LA Alvarenga, M Ribeiro, L Dai… - Nutrition …, 2021 - academic.oup.com
Sulforaphane (SFN) is a sulfur-containing isothiocyanate found in cruciferous vegetables
(Brassicaceae) and a well-known activator of nuclear factor-erythroid 2-related factor 2 …
(Brassicaceae) and a well-known activator of nuclear factor-erythroid 2-related factor 2 …
Nephroprotective activity of natural products against chemical toxicants: The role of Nrf2/ARE signaling pathway
E Molaei, A Molaei, F Abedi, AW Hayes… - Food Science & …, 2021 - Wiley Online Library
Nephropathy can occur following exposure of the kidneys to oxidative stress. Oxidative
stress is the result of reactive oxygen species (ROS) formation due to intracellular …
stress is the result of reactive oxygen species (ROS) formation due to intracellular …
[HTML][HTML] Preclinical investigations on broccoli-derived sulforaphane for the treatment of ophthalmic disease
Vision loss causes a significant burden on individuals and communities on a financial,
emotional and social level. Common causes include age-related macular degeneration …
emotional and social level. Common causes include age-related macular degeneration …
[HTML][HTML] Therapeutic implications of inflammasome in inflammatory bowel disease
V Khatri, R Kalyanasundaram - FASEB journal: official publication …, 2021 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) remains a persistent health problem with a global burden
surging over 6.8 million cases currently. Clinical pathology of IBD is complicated; however …
surging over 6.8 million cases currently. Clinical pathology of IBD is complicated; however …
[HTML][HTML] Interplay between phytochemicals and the colonic microbiota
C Kwon, MK Ediriweera, S Kim Cho - Nutrients, 2023 - mdpi.com
Phytochemicals are natural compounds found in food ingredients with a variety of health-
promoting properties. Phytochemicals improve host health through their direct systematic …
promoting properties. Phytochemicals improve host health through their direct systematic …