[HTML][HTML] Improvements in gene editing technology boost its applications in livestock

IV Perisse, Z Fan, GN Singina, KL White… - Frontiers in …, 2021 - frontiersin.org
Accelerated development of novel CRISPR/Cas9-based genome editing techniques
provides a feasible approach to introduce a variety of precise modifications in the …

Genetic engineering of livestock: the opportunity cost of regulatory delay

AL Van Eenennaam… - Annual Review of …, 2021 - annualreviews.org
Genetically engineered (GE) livestock were first reported in 1985, and yet only a single GE
food animal, the fast-growing AquAdvantage salmon, has been commercialized. There are …

Defective platelet activation in Gαq-deficient mice

S Offermanns, CF Toombs, YH Hu, MI Simon - Nature, 1997 - nature.com
Platelets are small disc-shaped cell fragments which undergo a rapid transformation when
they encounter vascular damage. They become more spherical and extrude pseudopodia …

Genetic constructs for delaying or repressing the expression of a target gene

MW Graham - US Patent 6,573,099, 2003 - Google Patents
The present invention relates generally to synthetic genes for modifying endogenous gene
expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic …

Cloned transgenic cattle produce milk with higher levels of β-casein and κ-casein

B Brophy, G Smolenski, T Wheeler, D Wells… - Nature …, 2003 - nature.com
To enhance milk composition and milk processing efficiency by increasing the casein
concentration in milk, we have introduced additional copies of the genes encoding bovine β …

Expression pattern of Oct-4 in preimplantation embryos of different species

N Kirchhof, JW Carnwath, E Lemme… - Biology of …, 2000 - academic.oup.com
POU transcription factors are involved in transcriptional regulation during early embryonic
development and cell differentiation. Oct-4, a member of this family, has been shown to be …

Transgenic production of antibodies in milk

H Meade, P DiTullio, D Pollock - US Patent 5,827,690, 1998 - Google Patents
US5827690A - Transgenic production of antibodies in milk - Google Patents US5827690A -
Transgenic production of antibodies in milk - Google Patents Transgenic production of …

Successful piglet production after transfer of blastocysts produced by a modified in vitro system

K Kikuchi, A Onishi, N Kashiwazaki… - Biology of …, 2002 - academic.oup.com
Porcine in vitro production (IVP) systems, including in vitro maturation (IVM) and in vitro
fertilization (IVF) of oocytes and their subsequent in vitro culture (IVC), have been modified …

Transgenic production of antibodies in milk

H Meade, P DiTullio, D Pollock - US Patent 5,849,992, 1998 - Google Patents
US5849992A - Transgenic production of antibodies in milk - Google Patents US5849992A -
Transgenic production of antibodies in milk - Google Patents Transgenic production of …

Advanced assisted reproduction technologies (ART) in goats

H Baldassarre, CN Karatzas - Animal Reproduction Science, 2004 - Elsevier
Assisted reproduction technologies (ART) are reviewed with special emphasis on goat
genetic improvement programs. Estrous synchronization and artificial insemination are the …